Natural Marine Anti-inflammatory Products

Abad, María J. F.; Bedoya, Luis Miguel; Bermejo, Paulina

doi:10.2174/138955708784912148

Cited by 88 publications

(54 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…in order to survive. Their economic potential is important in some areas of the globe, with Asia considering them as a central part of their diet (wakame, kombu) and Europe using them as a source of fertilizers, cosmetics, pharmacological products, and defense elicitors (Klarzynski et al, 2000;Abad et al, 2008;Holtkamp et al, 2009).…”

mentioning

confidence: 99%

Auxin Metabolism and Function in the Multicellular Brown AlgaEctocarpus siliculosus

et al. 2010

View full text Add to dashboard Cite

Ectocarpus siliculosus is a small brown alga that has recently been developed as a genetic model. Its thallus is filamentous, initially organized as a main primary filament composed of elongated cells and round cells, from which branches differentiate. Modeling of its early development suggests the involvement of very local positional information mediated by cell-cell recognition. However, this model also indicates that an additional mechanism is required to ensure proper organization of the branching pattern. In this paper, we show that auxin indole-3-acetic acid (IAA) is detectable in mature E. siliculosus organisms and that it is present mainly at the apices of the filaments in the early stages of development. An in silico survey of auxin biosynthesis, conjugation, response, and transport genes showed that mainly IAA biosynthesis genes from land plants have homologs in the E. siliculosus genome. In addition, application of exogenous auxins and 2,3,5-triiodobenzoic acid had different effects depending on the developmental stage of the organism, and we propose a model in which auxin is involved in the negative control of progression in the developmental program. Furthermore, we identified an auxin-inducible gene called EsGRP1 from a small-scale microarray experiment and showed that its expression in a series of morphogenetic mutants was positively correlated with both their elongated-to-round cell ratio and their progression in the developmental program. Altogether, these data suggest that IAA is used by the brown alga Ectocarpus to relay cell-cell positional information and induces a signaling pathway different from that known in land plants.

show abstract

mentioning

confidence: 99%

Auxin Metabolism and Function in the Multicellular Brown AlgaEctocarpus siliculosus

et al. 2010

View full text Add to dashboard Cite

show abstract

“…Numerous in vitro and in vivo studies have documented with anti-oxidant and anti-inflammatory activities of marine algae. 32 Ecklonia cava (Phaeophyceae; Laminareaceae), also known as ''sea trumpet", has been reported to possess anti-inflammatory activity. 33 E. cava was also able to suppress the levels of pro-inflammatory mediators such as nitric oxide (NO), prostaglandin-E2 (PGE2) and pro-inflammatory cytokines such as interleukin-6 (IL-6), interleukin-1β (IL-1β) and tumor necrosis factor-α (TNF-α).…”

Section: Biochemical Action Of Neuroprotective Marine Algaementioning

confidence: 99%

Phytochemicals Having Neuroprotective Properties from Dietary Sources and Medicinal Herbs

Kumar¹,

Anilakumar²,

Naveen³

2015

View full text Add to dashboard Cite

Many neuropsychiatric and neurodegenerative disorders, such as Alzheimer's disease, anxiety, cerebrovascular impairment, depression, seizures, Parkinson's disease, etc. are predominantly appearing in the current era due to the stress full lifestyle. Treatment of these disorders with prolonged administration of synthetic drugs will lead to severe side effects. In the recent years, scientists have focused the attention of research towards phytochemicals to cure neurological disorders. Nootropic herb refers to the medicinal role of various plants/parts for their neuroprotective properties by the active phytochemicals including alkaloids, steroids, terpenoids, saponins, phenolics, flavonoids, etc. Phytocompounds from medicinal plants play a major part in maintaining the brain's chemical balance by acting upon the function of receptors for the major inhibitory neurotransmitters. Medicinal plants viz. Valeriana officinalis, Nardostachys jatamansi, Withania somnifera, Bacopa monniera, Ginkgo biloba and Panax ginseng have been used widely in a variety of traditional systems of therapy because of their adaptogenic, psychotropic and neuroprotective properties. This review highlights the importance of phytochemicals on neuroprotective function and other related disorders, in particular their mechanism of action and therapeutic potential.

show abstract

“…In marine research, it is found that some natural products contain antioxidants with anti-inflammatory activities [29]. A compound isolated from green algae, Dunaliella bardawil (rich in b-carotene), had shown protective effects against acetic-acid-induced small bowel inflammation in rats [30].…”

Section: Anti-inflammatory Assaysmentioning

confidence: 99%