Natural Killer Cells: A Review on Their Role in Cancer Immunotherapy

Concise Review: Human Pluripotent Stem Cells to Produce Cell-Based Cancer Immunotherapy

“…Allogeneic NK cells from PB and UCB have been proven to be both safe and effective in multiple clinical studies . Optimization of NK cell development from hESC and iPSCs and clinical scale expansion of NK cells provides a platform for future clinical studies .…”

“…Allogeneic NK cell‐based therapy can be delivered in either a non‐transplant or transplant setting . In a non‐transplant setting, adoptive transfer of ex vivo expanded HLA‐haploidentical NK cells were used to treat patients with relapsed/refractory AML followed up with administration of IL‐2 .…”