Natural History of Psoriasis: A Study from the Indian Subcontinent

Abstract

Clinical and epidemiological data from 1220 patients with psoriasis is presented. Psoriatics accounted for 2.3% of the total dermatology outpatients. There was a distinct male preponderance. Mean age of onset was lower in women at 27.6 years, although the severity of the disease was the same in both sexes. Family history was positive in just 2% of patients. Plaque type disease was the most common, seen in over 93% of the patients. Lesional pruritus was a problem in 65%. Remission in summer was experienced by 43%. The scalp was the first site of onset in 25.2%. Nail and joint involvement were seen in 55.7% and 4.4%, respectively. Complete remission of disease activity was experienced by 35% of the patients during some part of the year in the course of their disease.

Histopathologic diagnostic parameters of psoriasis; a clinicopathological study

“…11 Similarly, Kaur I et al and Zlotogorski A studies reported improvement of skin lesions in summer as compared to winter. 9,12 In the present study 36.66% of cases presented during winter season followed by autumn and summer (25% and 21.67%).…”

“…8 Kaur I et al study revealed that mucosal involvement was uncommon in psoriasis. 9 Alhumidi study stated that the common body site involvement was lower extremity (42%), followed by upper extremity (27%), back (22%), Abdomen (18%), genitalia (9%), scalp (8%) and nail (2%). 6 In the current study, the commonest site was lower limb (90%), followed by upper limb (75%) and back (43.33%).…”

Retrospective Analysis of Clinical and Sociodemographic Features of Patients with Psoriasis

“…Hastalık başlangıç yaşları açısından yapılan araştır-malarda beyaz ırk, Hindistan, Japonya'da kadınlar-da hastalığın daha erken ortaya çıktığı görülmüştür (11,14,15) . Na ve ark.…”

Early intervention in psoriasis and immune-mediated inflammatory diseases: A hypothesis paper

“…In another study, persistent disease remission was observed in 17% of patients after 5 years, in 14% after 10 years and in 6% after 20 years (114). Complete clearance without treatment during some part of the year was reported by about one-third of patients in a study conducted in the Indian subcontinent (115). In most studies, sunlight exposure, summer, or a warm temperate climate are associated with disease improvement.…”