Natural course of articular chondrocalcinosis

Zitnan, D; Sitaj, S

doi:10.1002/1529-0131(197605/06)19:3+<363::aid-art1780190710>3.0.co;2-9

Cited by 71 publications

(2 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…There was no overall difference in the prevalence ofradiological osteoarthrosis between the gouty and control groups, but most of the patients with chondrocalcinosis showed evidence of osteoarthrosis of the knees. This may have been secondary to chondrocalcinosis (Hamilton, 1976;Zitnan and Sitaj, 1976;Resnick et al, 1977). An association with tophaceous deposition and renal impairment, claimed by other investigators (Dodds and Steinbach, 1966;Alarcon-Segovia and Garza, 1969) is not supported by the present study.…”

Section: Discussioncontrasting

confidence: 65%

Frequency of Chondrocalcinosis of the Knees and Avascular Necrosis of the Femoral Heads in Gout, a Controlled Study

Stockman¹,

Darlington

Scott

1980

Advances in Experimental Medicine and Biology

View full text Add to dashboard Cite

An association between urate gout and chondrocalcinosis has been suggested in several studies, but the situation remains ill-defined because of lack of appropriate controls, small numbers of patients studied, or retrospective investigation. An association has also been claimed between gout and avascular necrosis of the femoral head. 138 patients with gout and 142 non-gouty control subjects were carefully matched for age and x-rays were taken of the knees and pelvis. Chondrocalcinosis of the knees was detected in 8 patients with gout (5.8 %), no cases being found in the control group. The difference is significant (P<0 '025). Deposits were linear or irregular. Six of the 8 patients gave a history of acute synovitis of the knees; fluid had been aspirated in 2 of them, urate crystals being found in one and no crystals in the other. Six of the 8 patients showed evidence of chondrocalcinosis elsewhere. No association was apparent between chondrocalcinosis and the presence of tophaceous deposits or renal impairment, though the duration of gout appeared to be longer in the patients with chondrocalcinosis than in the other gout patients and osteoarthrosis of the knees commoner. There was no evidence of other metabolic disorders commonly associated with chondrocalcinosis. No cases of avascular necrosis of the femoral head were found.Despite considerable research into chondrocalcinosis in recent years its pathogenesis remains obscure. An association has been reported with various metabolic disorders such as hyperparathyroidism (McCarty, 1972), haemochromatosis (Dymock et al., 1970, and gout (Dodds and Steinbach, 1966). The association between gout and chondrocalcinosis remains ill defined because of the lack of appropriate controls, small numbers of patients, or retrospective study (Dodds and Steinbach, 1966;Good and Rapp, 1967).In studying 65 patients with 'idiopathic' avascular necrosis of femoral heads McCollum et al. (1967) found 13 patients with gout, urate crystals being demonstrated in synovial membrane from the hip in 6 of them. Serre et al. (1963) studied hips in 150 patients with gout and found 3 with non-traumatic avascular necrosis of the femoral head. In contrast Rotes Querol and Muno Gomez (1965) found no cases of avascular necrosis in 370 patients with gout.

show abstract

Section: Discussioncontrasting

confidence: 65%

Frequency of Chondrocalcinosis of the Knees and Avascular Necrosis of the Femoral Heads in Gout, a Controlled Study

Stockman¹,

Darlington

Scott

1980

Advances in Experimental Medicine and Biology

View full text Add to dashboard Cite

show abstract

“…The relationship between CPPD and imaging dates back to 1960, when radiographic findings associated with CPPD have been described under the term 'chondrocalcinosis', referring to the calcification of joint cartilage. Coined by Zitnan and Sitaj [32], Notably, ICD-11 introduces a dedicated code for CPPD disease for the first time. Updated from [4].…”

Section: Conventional Radiographymentioning

confidence: 99%

Describing calcium pyrophosphate deposition: undoing the tower of Babel!

Sirotti,

Terkeltaub,

Filippou

2024

Current Opinion in Rheumatology

View full text Add to dashboard Cite

Purpose of review In 1977, McCarty astutely observed, ‘The variety of names suggested for the condition associated with deposits of calcium pyrophosphate dihydrate crystals is exceeded only by the variations of its clinical presentation’. Fast forward to 2024, a standardized nomenclature for calcium pyrophosphate deposition (CPPD) is still lacking. This review aims to delineate the challenges in characterizing CPPD through nomenclature and imaging. Recent findings Despite the effort of nomenclature standardization in 2011 by the EULAR, confusion persists in the literature and clinical practice, with pseudo-forms and obscure abbreviations. The Gout, Hyperuricemia and Crystal-Associated Disease Network (G-CAN) has launched a project to redefine CPPD nomenclature and formulate a user-friendly language for effective communication with patients and other stakeholders. Additionally, recent advancements in imaging, have shed light on various aspects of the disorder. Summary Almost 60 years from the first description of a clinical manifestation related to calcium pyrophosphate crystals, a common language describing the disorder is still lacking. A redefined CPPD nomenclature, together with lay-friendly terminology, would significantly contribute to the uniformity of CPPD research, enhance public understanding and awareness and improve doctor-patient communication and therefore disease outcomes. Imaging can provide deep insights into CPPD elements, promoting comprehension of this disorder.

show abstract

Pyrophosphate Arthropathy in the Knees of Elderly Persons

Handy

1996

Arch Intern Med

View full text Add to dashboard Cite

show abstract

Natural course of articular chondrocalcinosis

Cited by 71 publications

References 12 publications

Frequency of Chondrocalcinosis of the Knees and Avascular Necrosis of the Femoral Heads in Gout, a Controlled Study

Frequency of Chondrocalcinosis of the Knees and Avascular Necrosis of the Femoral Heads in Gout, a Controlled Study

Describing calcium pyrophosphate deposition: undoing the tower of Babel!

Pyrophosphate Arthropathy in the Knees of Elderly Persons

Contact Info

Product

Resources

About