Natural antibiotic susceptibility of Enterobacter amnigenus, Enterobacter cancerogenus, Enterobacter gergoviae and Enterobacter sakazakii strains

Abstract

The present study establishes a database concerning the natural susceptibility of recently established Enterobacter species to a wide range of antibiotics, which can be applied for the validation of routine susceptibility test results. beta-Lactam susceptibility patterns indicate the expression of species-specific beta-lactamases expressed at high or low levels in all the species except E. sakazakii.

Cronobacter spp. – opportunistic food-borne pathogens. A review of their virulence and environmental-adaptive traits

“…Muytjens & van der Ros-van de Repe (1986) examined Cronobacter susceptibility to 29 antimicrobial agents and found that Cronobacter were the most susceptible among other Enterobacteriaceae studied. This was supported by the finding of Stock & Wiedemann (2002) who showed that Cronobacter were repeatedly susceptible to b-lactams with no evidence for the expression of b-lactamase. In contrast, Pitout et al (1997) demonstrated that some strains of Cronobacter produce b-lactamase at low levels.…”

Cronobacter sakazakii: stress survival and virulence potential in an opportunistic foodborne pathogen

“…Originally C. sakazakii has been reported to be susceptible to a wide range of antibiotics including b-lactams, 23 however, several new strains have been described that were found to be resistant to tetracycline, 24 neomycin and trimethoprim 25 and cephalotin. 26 Furthermore, recent studies have described a strain carrying an unusual ampC gene, conferring resistance to cephalosporine 27 and found environmental isolates of C. sakazakii from domestic kitchens exhibiting resistance to penicillin, tetracycline, ciprofloxacin and nalidixic acid.…”

Phage therapy of Cronobacter-induced urinary tract infection in mice

“…The lethality of Cronobacter infections is very high (40-80%) and the incidence is relatively low (8.7 per 100 000 low birth weight neonates) [3,4]; however, it is assumed that the number of infections caused by Cronobacter is underreported. Antibiotic therapy is effective if applied soon after infection, but resistance against some therapeutics has already been reported [5]. It can be expected that alternative approaches will be needed soon, since the antimicrobial resistance is rising [6].…”