Natural and synthetic intense sweeteners

Sardesai, Vishwanath M.; Waldshan, Tammi H.

doi:10.1016/0955-2863(91)90081-f

Cited by 53 publications

(38 citation statements)

References 66 publications

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“…This sparked an increase in the use of sugar worldwide. [1] Today, there is an extensive choice of sweeteners available to the consumer. These sweeteners can be categorised into either nutritive (natural sweeteners) or non-nutritive sweeteners (artificially manufactured sweeteners).…”

Section: Introductionmentioning

confidence: 99%

“…[9] Diabetic patients and individuals wanting to control their weight have access to these products that allow them the pleasure of a sweettasting treat without adverse health effects. [1] These alternate sweeteners are used extensively as additives in food, beverages, confectionary, and in the pharmaceutical sector. Common types of artificial sweeteners include aspartame, acesulfame-K, cyclamate, neotame, sucralose, and saccharin.…”

Section: Introductionmentioning

confidence: 99%

“…As a result, this created a demand for the development of alternate sweeteners, which offer a low-calorie intake. [1] The manufacture of artificial sweeteners by the food industry, promised consumers the sweetness of sugar without the calories. [9] Diabetic patients and individuals wanting to control their weight have access to these products that allow them the pleasure of a sweettasting treat without adverse health effects.…”

Section: Introductionmentioning

confidence: 99%

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THEIN VITROEFFECTS OF ARTIFICIAL AND NATURAL SWEETENERS ON THE IMMUNE SYSTEM USING WHOLE BLOOD CULTURE ASSAYS

Rahiman

Pool

2013

Journal of Immunoassay and Immunochemistry

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. The in vitro effects of artificial and natural sweeteners on the immune system using whole blood culture assays. The in vitro effects of artificial and natural sweeteners on the immune system using whole blood culture assays F. Rahiman and E. J. Pool AbstractThis article investigates the effects of commercially available artificial (aspartame, saccharin, sucralose) and natural sweeteners (brown sugar, white sugar, molasses) on the immune system. Human whole blood cultures were incubated with various sweeteners and stimulated in vitro with either phytohemagglutinin or endotoxin. Harvested supernatants were screened for cytotoxicity and cytokine release.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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THEIN VITROEFFECTS OF ARTIFICIAL AND NATURAL SWEETENERS ON THE IMMUNE SYSTEM USING WHOLE BLOOD CULTURE ASSAYS

Rahiman

Pool

2013

Journal of Immunoassay and Immunochemistry

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“…The compound miraculin, although not sweet, has the property of modifying the taste of sour food into a delightfully sweet taste. The artificial sweeteners currently in use are saccharin, aspartame, and acesulfame K, sucralose [28].…”

Section: Sweeteners: Importance Definition Types Requirements Safetymentioning

confidence: 99%

Stevia Derivative and its Potential Uses in Diabetic-Directed Foods. Review

Pérez

González

Vaillant

et al. 2016

Journal of Nutrients

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“…Aspartame is currently considered as safe artificial sweetener and now is the most popular sweetener in more than 75 countries that may be used separately or in combination with other sweeteners 2 . This sweetener is a dipeptide L-aspartyl-L-phenylalanine methyl ester 3,5 that its sweetness accidently discovered in 1965 by James M. Schlatter 5 . Aspartame is composed of phenylalanine, aspartic acid plus a small amount of methanol 6 .…”

Section: Introductionmentioning

confidence: 99%

Assessment of Aspartame Exposure Due to Consumption of Some Imported Chewing Gums by Microwave Digestion and High Performance Liquid Chromatography Analysis

Rasouli¹,

Akbari‐adergani²

2016

Orient. J. Chem

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Aspartame is a widely used artificial sweetener, the long-term safety of which has been controversial ever since it was accepted for human consumption. The main aim of this research is assessment of aspartame exposure due to consumption of some imported chewing gums during summer 2015 to Iran by microwave digestion and HPLC analysis. Thirty chewing gums from highly consumed imported ones were collected from retail market in Tehran. Closed vessel microwave digestion was employed for sample preparation using a three phase temperature program. An aliquot of 20 µL of prepared samples was injected into the HPLC column and the aspartame was detected at 254 nm with an on-line detector. Concentration of aspartame in chewing gum samples was between 1.9 and 30.5 µg/g with an average of 11.1 µg/g. In conclusion, despite of existing aspartame in 76.6 percent of samples, however the effective amount of this artificial sweetener is not as high as the levels that international legislations recommended for exposing due to chewing gum consumption.

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Natural and synthetic intense sweeteners

Cited by 53 publications

References 66 publications

THEIN VITROEFFECTS OF ARTIFICIAL AND NATURAL SWEETENERS ON THE IMMUNE SYSTEM USING WHOLE BLOOD CULTURE ASSAYS

THEIN VITROEFFECTS OF ARTIFICIAL AND NATURAL SWEETENERS ON THE IMMUNE SYSTEM USING WHOLE BLOOD CULTURE ASSAYS

Stevia Derivative and its Potential Uses in Diabetic-Directed Foods. Review

Assessment of Aspartame Exposure Due to Consumption of Some Imported Chewing Gums by Microwave Digestion and High Performance Liquid Chromatography Analysis

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