Native Valve Endocarditis due to<i> Staphylococcus warneri</i> Developing in a Patient with Type 1 Diabetes

Abstract

A 59-year-old man with type 1 diabetes presented with heart failure. Echocardiography showed large vegetations on the mitral and aortic valves. Blood bacterial culture was positive for Staphylococcus warneri , a coagulase-negative staphylococcus (CoNS) family member. He was diagnosed with native valve endocarditis (NVE) induced by the resident bacteria and ultimately underwent double valve replacement. Retrospectively, slight laboratory data abnormalities and weight loss beginning four months before may have been signs of NVE. He had no history of immunosuppressive therapies or medical device implantation. Thus, CoNS can cause NVE after a long asymptomatic course in patients with poorly controlled diabetes.

Distribution and antibiotic-resistance of different Staphylococcus species identified by matrix assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) isolated from the oral cavity

“…The discrepancy between our findings and the results of the studies mentioned above may result from differences in patient groups, methods of staphylococci isolation and identification, and geographic region. S. warneri was previously reported as a cause of catheter-related bacteriemia, endocarditis, multiple abscesses, and septic arthritis [ 26 , 27 ]. S. saprophyticus and S. haemolyticus are considered harmful hospital pathogens that cause severe infections with a significant level of bacteraemia [ 28 ].…”

Native mitral valve infective endocarditis caused by Staphylococcus warneri: A case‐based review

“…To our best of knowledge, there were only 12 case reports, including our case, on IE caused by S. warneri in the English language literature (Table 1). [13][14][15][16][17][18][19][20][21][22] The cases had a mean age of 56 years (range, 32-79 years), and 3 of 12 cases were women. In Table 1, 7 of 12 patients (58.3%) without medical prosthesis developed IE.…”

Native mitral valve infective endocarditis caused by Staphylococcus warneri: A case-based review

“…First, S. warneri can cause IE in a patient with valvular heart disease without medical device. To our best of knowledge, there were only 12 case reports, including our case, on IE caused by S. warneri in the English language literature (Table 1) [12][13][14][15][16][17][18][19][20][21][22] . The cases had a mean age of 56 years (range, 32-79 years), and 3 of 12 cases were women.…”