Nationwide survey on adult type chronic intestinal pseudo-obstruction in surgical institutions in Japan

Abstract

The segments of the diseased bowels should be considered in determining the indications for surgical treatments in CIP patients.

Chronic Intestinal Pseudo-obstruction: Clinical and Manometric Characteristics in the Chilean Population

“…As in other studies with a similar number of patients, a predominance of females was observed, and most of the cases corresponded to primary CIPO. 4,10,12,13 The average age of our patients at diagnosis was similar to that described in European studies 12 and significantly younger than the age observed in Japanese studies. This is probably due to enrollment of patients with colonic involvement, which appear at an older age.…”

“…In the work by Masaki et al, 4 the distribution was reversed with the colon appearing compromised most frequently, and the least common disorder being the small intestine.…”

“…A study showed that the results of surgical treatment were better in the presence of isolated colon compromise and less effective in the presence of both compromised small intestine and colon. 4 Some authors 16 have analyzed the evolution of a large group of patients with CIPO undergoing non-transplant surgery, observing that surgical treatment was associated with high mortality (7.9%) and morbidity (58.2%); the latter associated with intraoperative intestinal lesions, idiopathic CIPO, and emergency surgery, and concluded that efforts should be made to avoid surgery, if possible.…”

“…It is characterized by a failure of the propulsion of intraluminal contents due to the inability to generate a suitable motor "pattern," either due to a deficit of the contractile force or of the coordination of the waves. [1][2][3][4][5] Clinically there are recurrent episodes characterized by symptoms, clinical signs, and images of partial bowel obstruction in the absence of a mechanical obstruction, which often lead to performing unnecessary surgeries. The clinical picture usually has a progressive nature, in which important abdominal symptoms appear, such as pain, bloating, and distension, associated with alterations of intestinal transit and weight loss.…”

“…The clinical picture usually has a progressive nature, in which important abdominal symptoms appear, such as pain, bloating, and distension, associated with alterations of intestinal transit and weight loss. [1][2][3][4][5] Frequently the presence of intestinal bacterial overgrowth is suspected and the patients are treated with antibiotics, although this phenomenon has rarely been studied systematically. 6,7 The progression of the illness is usually associated with malabsorption and malnutrition, sometimes becoming necessary to resort to parenteral nutrition.…”