Nationwide Survey of Malignant Melanoma (1992-1998).

和之, 石原; 俊明, 斎田; 明史, 山本

doi:10.5227/skincancer.15.7

Cited by 5 publications

(4 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Although malignant melanoma is a relatively rare disease in Asia, the incidence of melanoma is increasing. In a nationwide survey of 4495 cases of melanoma from 1992 to 1998 in Japan, the incidence of the disease increased 5-folds [ 16 ]. A similar pattern was observed in the metropolitan areas in China, although systemically established tumor registry is lacking.…”

Section: Discussionmentioning

confidence: 99%

Clinical presentation, histology, and prognoses of malignant melanoma in ethnic Chinese: A study of 522 consecutive cases

et al. 2011

View full text Add to dashboard Cite

BackgroundMalignant melanoma is a rare disease in Asia, and knowledge on its characteristics and clinical outcome in Asian patients is limited. The purpose of this observational study was to determine the clinical presentation and outcome of patients with melanoma in China.MethodsA database was prospectively established for the purpose of this analysis. The elements of the database included basic demographic data of patients and prognosticators previously reported in literature, as well as follow-up data including clinical outcome after treatment. Medical record of all patients with pathologically diagnosed malignant melanoma consulted in our center since 2006 were retrieved and reviewed. No patient was excluded in this study. Statistical analyses including survival and multivariate analyses of factors associated with survival were respectively performed by Kaplan-Meier method and Cox proportional hazard model.ResultsA total of 522 consecutive and nonselected cases were evaluated. There were 218 cases (41.8%) of acral lentiginous melanoma (ALM), 118 (22.6%) of mucosal melanoma (MCM), 103 (19.7%) of nodular melanoma (NM), 33 (6.3%) of superficial spreading melanoma (SSM), and others were Lentigo maligna melanoma or unclassifiable disease. The proportion of patients with clinical stage I, II, III, and IV diseases were 6.1%, 55.9%, 25.1%, and 12.8%, respectively. Among the 357 cases of cutaneous melanoma, 234 patients (65.5%) had ulceration.The 5-year overall survival rate of all 522 patients was 41.6%, and the median survival time was 3.92 years (95% CI, 3.282 to 4.558). Five-year survival rates of patients with stage I, II, III, and IV diseases were 94.1%, 44.0%, 38.4% and 4.6% respectively (P < 0.001). Multivariate analysis revealed that clinical stage and the ulceration were two significant prognosticators for OS. In addition, extent of surgery and use of adjuvant therapy were significant prognosticators for DFS in patients with non-metastatic disease after definitive treatment. Pathological subtype was not a significant prognostic factor to predict wither OS or DFS.ConclusionsPrognoses of patients with malignant melanoma diagnosed in China were suboptimal, and most patients were diagnosed with locally advanced disease (i.e., stage II or above). ALM and MCM are the two most commonly diagnosed pathological subtypes. Clinical staging and presence of ulceration was significantly associated with clinical outcome in terms of OS, while treatment strategy including extent of surgery and use of adjuvant therapy were significant predictors of DFS.

show abstract

Section: Discussionmentioning

confidence: 99%

Clinical presentation, histology, and prognoses of malignant melanoma in ethnic Chinese: A study of 522 consecutive cases

et al. 2011

View full text Add to dashboard Cite

show abstract

“…Since 1987, the Prognosis and Statistical Investigation Committee of the Japanese Skin Cancer Society has taken the lead in performing nationwide surveys. [3][4][5][6][7][8] In an article published in 2001, 7 we reported the results of nationwide epidemiological surveys of skin cancers in Japan. In the present article, we report the latest updated data of our study.…”

Section: Introductionmentioning

confidence: 99%

“…The number of patients with superfi cial spreading melanoma (SSM) increased steadily over time and exceeded the number of patients with nodular melanoma (NM) in group C. The prognosis of NM was the worst, while that of SSM was the most favorable. (6) The proportion of stage I patients was larger in group C than in groups A and B, but no signifi cant difference among the groups was observed in the proportions of stage II, III, and IV patients. For patients in stage III, the overall survival rate was higher in group C than that in group A or B, while there was no apparent difference in survival between the groups for patients in stage I or II.…”

mentioning

confidence: 95%

Statistical profiles of malignant melanoma and other skin cancers in Japan: 2007 update

Saida²,

et al. 2008

Self Cite

View full text Add to dashboard Cite

show abstract

“…However, the neoplasm is relatively uncommon among Asians, Hispanics and Africans [2]. A study from Japan reported a rising incidence of malignant melanoma [3]. A study from China which reviewed 522 patients with malignant melanoma found that most patients presented with locally advanced disease and had suboptimal prognosis.…”

Section: Discussionmentioning

confidence: 99%

Malignant Melanoma Presenting as Bilateral Pleural Effusion

Singh¹,

Vk²

2015

JCR

View full text Add to dashboard Cite

Abstract:Malignant melanoma is a common malignancy in Western population especially in light skinned people although it is relatively uncommon in India. Pleural effusion is an unusual presentation of malignant melanoma. We present the case of a 45 year old patient who presented with chest pain and dyspnea. Computed tomography scan of chest revealed bilateral pleural effusion. Cytological examination of pleural fluid was found to contain malignant epithelial cells. Fine needle aspiration cytology of ulcero-proliferative lesion in left sole was suggestive of malignant melanoma. The patient was treated with chemical pleurodesis but he succumbed to progressive disease after six months.

show abstract

Nationwide Survey of Malignant Melanoma (1992-1998).

Cited by 5 publications

References 2 publications

Clinical presentation, histology, and prognoses of malignant melanoma in ethnic Chinese: A study of 522 consecutive cases

Clinical presentation, histology, and prognoses of malignant melanoma in ethnic Chinese: A study of 522 consecutive cases

Statistical profiles of malignant melanoma and other skin cancers in Japan: 2007 update

Malignant Melanoma Presenting as Bilateral Pleural Effusion

Contact Info

Product

Resources

About