Nationwide survey of extended-spectrum β-lactamase-producing Enterobacteriaceae in the French community setting

Abstract

This first nationwide study reports an ESBLE prevalence of 1.1% in the French community setting in 2006, mainly related to the presence of CTX-M-producing E. coli strains; furthermore, unusual co-resistances rarely found in the community setting were occasionally observed, which may threaten future emergence.

Characterization of extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae isolates from the community in Morocco

“…The prevalence of 1.3% ESBL-producing E. coli in the community found in this study is similar to that recorded in Spanish and French communities (1.4%) (Arpin et al, 2009;Rodríguez-Baño et al, 2004) but lower than the 5.2% observed in a Spanish multicentre study covering 15 microbiology laboratories in 2006 (Andreu et al, 2008). A study performed in Turkey showed a prevalence of 21% ESBL producers among E. coli causing communityacquired urinary tract infections during (Yumuk et al, 2008.…”

“…The co-existence of different b-lactamases genes within the same isolate, as detected in this study, has also been reported in other countries (Arpin et al, 2009;Woodford et al, 2007). The combination of bla CTX-M-15 +bla OXA-1 +bla TEM-1b was reported in 30 strains from Portugal (Mendonça et al, 2007), and an association between bla SHV-5 and bla TEM-1b has been described in the Brazilian community (Minarini et al, 2007a).…”

“…The CTX-M type was the most common ESBL in our setting. The predominance of CTX-M-15 indicates that this allele is now common in Morocco, as in other countries as a result of worldwide dissemination (Arpin et al, 2009;Minarini et al, 2007a;Woodford et al, 2007). These higher rates of CTX-M among total ESBL enzymes are most probably associated with high mobilization of the encoding genes.…”

“…CTX-M-producing Escherichia coli and Klebsiella pneumoniae are becoming increasingly involved in urinary tract infections, especially among outpatients. Furthermore, these bacteria seem to have been imported from the community into the hospital setting (Arpin et al, 2009).…”

Diversity of Escherichia coli Strains Producing Extended-Spectrum β-Lactamases in Spain: Second Nationwide Study

“…In a similar study developed in 2006 in the French community setting, the percentage of CTX-M-producing ESBLEC was much higher (83%). SHV-12 was expressed only in 1 of 48 isolates (1). ESBL distribution in Spain is different from that observed in other countries, underlining the great epidemiological variability of these resistance determinants and the need to study them under different epidemiological conditions.…”