Nasoseptal perforation secondary to lupus vulgaris

Matsumoto, Fernando Yoshiaki; Brandt, Hebert Roberto Clivati; Martins, José Eduardo; Rivitti, Evandro A.; Romiti, Ricardo

doi:10.1111/j.1346-8138.2007.00318.x

Cited by 8 publications

(5 citation statements)

References 7 publications

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“…Extension to involve anterior nasal cartilage of the nasal septum and anterior end of turbinates has been reported. [ 3 ] The resultant atrophic scarring following ATT may lead to extensive deformity and mutilation along with fibrotic contractures. [ 4 ]…”

Section: Discussionmentioning

confidence: 99%

Lupus vulgaris leading to perforation of nasal septum in a child

Singal

Arora

Pandhi

2015

Indian Dermatol Online J

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Lupus vulgaris (LV) is a common form of cutaneous tuberculosis in India, mostly involving the lower half of the body. Facial involvement is uncommon. Untreated disease may lead to significant morbidity due to atrophic scarring, mutilation, and deformity. We report a case of multi-focal LV in a 10-year-old boy affecting the nose and cheek that resulted in perforation of the nasal septum, a rarely reported complication.

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Section: Discussionmentioning

confidence: 99%

Lupus vulgaris leading to perforation of nasal septum in a child

Singal

Arora

Pandhi

2015

Indian Dermatol Online J

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“…PCR has been effectively used in the diagnosis of cutaneous tuberculosis in immunocompromised patients; but its usefulness in immunocompetent patients with paucibacillary forms of tuberculosis remains controversial 3,4,7 . Delays in initiating therapy in undiagnosed, long‐standing cases result in considerable morbidity including squamous cell carcinoma, nasal perforation, disfiguring scars, and so on 8–11 …”

Section: Discussionmentioning

confidence: 99%

“…3,4,7 Delays in initiating therapy in undiagnosed, long-standing cases result in considerable morbidity including squamous cell carcinoma, nasal perforation, disfiguring scars, and so on. [8][9][10][11] A therapeutic trial of ATT is worth trying in difficult cases where definitive diagnosis is not forthcoming despite the potential adverse effects of ATT. 1,6,12 Hence, empiric treatment after taking into consideration the entire clinical setting may be the only option left with the clinician faced with this complex if not daunting clinical entity.…”

Section: Discussionmentioning

confidence: 99%

Atypical forms of lupus vulgaris – a case series

et al. 2009

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Atypical presentations of cutaneous tuberculosis are not so uncommon and are frequently overlooked in clinical practice, leading to late diagnosis and increased morbidity. We report three cases of lupus vulgaris with atypical presentations. The cases mimicked other chronic skin lesions like actinomycosis, mycetoma, and so on. Strong clinical suspicion, histopathology, and response to antituberculous treatment led to the diagnosis and all three had excellent response to treatment. Today, when tuberculosis threatens to burst into pandemics again, early diagnosis and treatment are more important than ever for control and prevention of morbidity.

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“…Complications related to long‐standing LV include lymphoedema, contractures and mutilations, and malignancies, which commonly include squamous cell carcinoma (SCC), and more rarely basal cell carcinoma, Bowen’s disease, syringoid eccrine carcinoma, melanoma and lymphoma 3 . Ulcerative LV involving the face, the commonest site in developed countries, may give rise to nasoseptal perforation as well 4 …”

Section: Discussionmentioning

confidence: 99%

Chronic nonhealing ulcer on the hand

De¹,

Khadwal²,

Singhi³

et al. 2009

Clinical and Experimental Dermatology

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A 12-year-old boy presented with a progressive chronic ulcer over the left hand of 6 yearsÕ duration. The lesion had started as a skin-coloured papule over the dorsum of the left hand. It later ulcerated and gradually extended over a number of years to the adjacent area at one end and healing with scarring at the other. This led to fusion of the middle three fingers of the left hand, causing difficulty with movement. The lesion was not preceded by any local trauma or bite. He was from poor socioeconomic background and his immunization was incomplete. There was a history of weight loss for past 2 years.On physical examination, the patient was found to have mild pallor and bilateral submandibular and posterior cervical lymphadenopathy, with no systemic abnormalities. There was atrophic, hypopigmented, Ôcigarette paperÕ-like scar involving the dorsum of the left hand merging with the ulcer. A large well-defined, irregularly bordered, painless ulcer with adhesion to the underlying bone was present, involving the dorsum of the left hand, and the index, middle and ring fingers, extending to the distal part of the palm. (Fig. 1a,b) The involved three fingers were fused with each other proximally due to extensive granulation tissue and necrotic slough, distorting the finger morphology. The patient also had pediculosis capitis and pyoderma over his face. Figure 1 Well-defined, irregularly bordered, painless ulcer involving the dorsum of the left hand and the index, middle and ring fingers. Note the hypopigmented atrophic scarred patch proximal to the ulcer.

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Nasoseptal perforation secondary to lupus vulgaris

Cited by 8 publications

References 7 publications

Lupus vulgaris leading to perforation of nasal septum in a child

Lupus vulgaris leading to perforation of nasal septum in a child

Atypical forms of lupus vulgaris – a case series

Chronic nonhealing ulcer on the hand

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