Narrowband UV-B produces superior clinical and histopathological resolution of moderate-to-severe psoriasis in patients compared with broadband UV-B

Narrowband UV-B Phototherapy vs Photochemotherapy in the Treatment of Chronic Plaque-Type Psoriasis

“…10,11 Several authors subsequently investigated the therapeutic effectiveness of narrowband UV-B by either comparing the treatment results for the new lamp with those from previous trials using broadband or by means of bilateral comparison studies. [13][14][15][16][17][18][19] These investigations confirmed the efficacy of narrowband UV-B treatment and showed that it provides for faster clearing, less burning reactions, and longer periods of remission 12 than conventional broadband UV-B phototherapy. The relative efficacy of narrowband UV-B in comparison to PUVA was investigated by van Weelden et al 20 in a pilot study of 10 patients with widespread psoriasis vulgaris.On average the same results were found with both treatments.…”

Interleukin-11 therapy selectively downregulates type I cytokine proinflammatory pathways in psoriasis lesions

“…This index grades individual psoriasis lesions for scale, erythema, and induration on a 0-to 6-point scale for each parameter (0, absent; 1, trace; 2, mild; 3, mild to moderate; 4, moderate; 5, moderate to severe; and 6, severe). The final score is the sum of the individual parameters for a range of 0-18 (26,27). Histopathological assessment was performed on onehalf of the 6-mm punch biopsy.…”

Basics and Biomedical Applications of Dielectric Barrier Discharge (DBD)

“…The irradiation of the treated surface by UV-A and UV-B in different discharge modes are shown in figure 11a and 11b respectively. Ultraviolet A (UV-A, 320 -400 nm) and ultraviolet B (UV-B, 280 -320 nm) are selectively used for treatment of skin diseases like psoriasis (Coven, 1997), atopic dermatitis (Krutmann, 1992), localized scleroderma (Stege, 1997) and vitiligo (Kumar, 2009). UVA-UVB therapy is more efficient than UV-B therapy for treating skin diseases like atopic dermatitis (Hannuksela, 1985& Jekler, 1990.…”