Narrowband ultraviolet B (311 nm, TL01) phototherapy in chronic ordinary urticaria

Aydoğan, Kenan; Karadogan, Serap Koran; Tunali, Şükran; Sarıcaoğlu, Hayriye

doi:10.1111/j.1365-4632.2011.05056.x

Cited by 31 publications

(26 citation statements)

References 36 publications

(60 reference statements)

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“…Several studies have assessed the use of UVR therapy in urticaria (Table ). In general, UVR therapy appears to be helpful in reducing the symptoms of urticaria, with PUVA and UVA and also PUVA and NB‐UVB showing comparable results. Recently, both PUVA and NB‐UVB were effective in steroid‐dependent antihistamine‐refractory chronic urticaria, with NB‐UVB being statistically better .…”

Section: Uv Treatment In Mast Cell‐driven Diseasesmentioning

confidence: 98%

“…Recently, both PUVA and NB‐UVB were effective in steroid‐dependent antihistamine‐refractory chronic urticaria, with NB‐UVB being statistically better . The use of different outcome measures such as visual analogue score, outcome scoring scale, urticaria activity score and quality of life impedes the direct comparison of studies …”

Section: Uv Treatment In Mast Cell‐driven Diseasesmentioning

confidence: 99%

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Ultraviolet radiation and skin mast cells: Effects, mechanisms and relevance for skin diseases

Siiskonen

Smorodchenko

Krause

et al. 2017

Experimental Dermatology

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Mast cells (MCs) are well known as versatile effector cells in allergic reactions and several other immune responses. Skin MCs and cutaneous MC responses are subject to the effects of environmental factors including ultraviolet radiation (UVR). Numerous studies have assessed the effects of UVR on MCs, in vitro and in vivo. Interestingly, UVR seems to have variable effects on non-activated and activated mast cells. In general, UV therapy is beneficial in the treatment of urticaria and mastocytosis, but the effects are variable depending on treatment regimen and type of UVR. Here, we review and summarise key reports from the older and current literature on the crosstalk of UVR and skin MCs. Specifically, we present the literature and discuss published reports on the effects of UVR on skin MCs in rodents and humans. In addition, we review the role of MCs in UVR-driven skin diseases and the influence of UV light on MC-mediated skin diseases. This summary of our current understanding of the interplay of skin MCs and UVR may help to improve the management of patients with urticaria and other MC disorders, to identify current gaps of knowledge, and to guide further research. K E Y W O R D Scancer, mast cell, ultraviolet radiation, urticaria

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Section: Uv Treatment In Mast Cell‐driven Diseasesmentioning

confidence: 98%

Section: Uv Treatment In Mast Cell‐driven Diseasesmentioning

confidence: 99%

Ultraviolet radiation and skin mast cells: Effects, mechanisms and relevance for skin diseases

Siiskonen

Smorodchenko

Krause

et al. 2017

Experimental Dermatology

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“…The current EAACI/GA(2)LEN/EDF/WAO guidelines recommend using omalizumab, ciclosporin, or montelukast in patients who are unresponsive to up to fourfold dosed non-sedating antihistamines [3]. Additional therapeutics that have been tried in CSU include colchicine [37], mesalazine [38], hydroxychloroquine [39], dapsone [40,41], sulfasalazine [42], corticosteroids [43], narrowband ultraviolet B phototherapy [44], doxepin [45,46], mycophenolate mofetil [47,48], methotrexate [49][50][51], plasmapheresis [52], miltefosine [53], and intravenous immunoglobulin (IVIG) [54][55][56]. The vast majority of these have been used in small case reports and case series, but not in randomized controlled trials (RCTs) [ Table 1].…”

Section: Second-line Agents For Csumentioning

confidence: 99%

Treatment of Severely Recalcitrant Chronic Spontaneous Urticaria: A Discussion of Relevant Issues

2014

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Chronic spontaneous urticaria (CSU) is a common disorder with a prevalence of 1% that is characterized by recurrent wheals, angioedema, or both. CSU is self-limited but in many patients symptoms recur for several years and can be refractory to standard therapies. In this review, we present an illustrative case of a female patient with CSU who, despite taking 15 antihistamines a day in addition to a number of second-line therapies, continued to be refractory to treatment. However, once we initiated subcutaneous treatment with omalizumab 300 mg every 4 weeks, she experienced rapid relief of her CSU symptoms. Through this case, we present a review of the relevant issues, including the efficacy of laboratory tests to identify the cause of a patient's CSU, the association between CSU and thyroid disease and its relevance to treatment options, the recommendation to increase antihistamine dose up to fourfold and possible adverse events associated with this treatment option. We also include a discussion of the use of second-line therapies as well as omalizumab in refractory CSU patients.

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“…Other treatment options that have significant activity on mediator release on basophils include the calcineurin inhibitor cyclosporin A [55–60], and occasionally ultraviolet therapy [59–62]. As for immunosuppressive therapy with cyclosporin, a recent study suggests that history of hives, shorter duration of urticaria (mean of 55.2 weeks versus 259.6 weeks, P = 0.03), and CU index >10 ( P = 0.05) predict a favorable response to cyclosporin [60].…”

Section: Treatment Optionsmentioning

confidence: 99%

Chronic Urticaria: Indian Context—Challenges and Treatment Options

Khan

Maitra²,

Hissaria

et al. 2013

Dermatology Research and Practice

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Urticaria is a common condition that occurs in both children and adults. Most cases have no specific allergic trigger and the aetiology of urticaria remains idiopathic and occasionally spontaneous in nature. Inappropriate advice such as avoidance of foods (milk, egg, prawn, and brinjal) is common place in certain sections of India mostly by nonspecialists that should not be routinely recommended. It is important to look for physical urticarias such as pressure urticaria in chronic cases, which may be present either alone or in combination with other causes. Autoimmune causes for chronic urticaria have been found to play an important role in a significant proportion of patients. Long-acting nonsedating antihistamines at higher than the standard doses is safe and effective. Quality of life is affected adversely in patients with chronic symptomatic urticaria and some may require multidisciplinary management.

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Narrowband ultraviolet B (311 nm, TL01) phototherapy in chronic ordinary urticaria

Cited by 31 publications

References 36 publications

Ultraviolet radiation and skin mast cells: Effects, mechanisms and relevance for skin diseases

Ultraviolet radiation and skin mast cells: Effects, mechanisms and relevance for skin diseases

Treatment of Severely Recalcitrant Chronic Spontaneous Urticaria: A Discussion of Relevant Issues

Chronic Urticaria: Indian Context—Challenges and Treatment Options

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