Naphthalimide Assemblies for Simultaneous Detection of Ferrous Ion and H₂O₂ to Prevent Fenton Reaction

Abstract

The supramolecular assemblies of naphthalimide derivative having morpholine and dihydropyridine units referred as Naph‐MDHP exhibit strong affinity for Fe2+ ions and H2O2 to generate ‘more ordered’ highly fluorescent architectures in aqueous medium. In the presence of supramolecular assemblies of Naph‐MDHP, the oxidation of Fe2+ ions and Fenton reaction is prevented, despite the co‐existence of Fe2+ ions and H2O2 as indicated by slow photocatalytic degradation of dye Methylene blue monitored by UV‐vis spectroscopic studies. The work presented in this manuscript reveals the real time application of naphthalimide assemblies to protect dopamine and DNA against iron‐H2O2 induced oxidative stress.

Study of a Fluorescent System Based on the Naphthalene Derivative Fluorescent Probe Bound to Al3+

“…This may be due to the fact that Al 3+ inhibits the formation of hydrogen bonds between N and H and the lone pair electron transfer of N, thus leading to a decrease in intramolecular proton transfer and excited state photoinduced electron transfer. This phenomenon restored the fluorescence intensity of the F6 probe [15,26,32].…”

“…fer and excited state photoinduced electron transfer. This phenom rescence intensity of the F6 probe [15,26,32].…”

“…However, compared with other metal ions, Al 3+ presents more difficulties in detection because of its poor coordination ability, strong hydration ability, and lack of spectral characteristics [12,13]. However, naphthalimide has the advantages of stable planar structure, large Stokes shift, high quantum yield, strong light resistance and low toxicity, so it is selected as a fluorescent group because of its excellent properties when constructing fluorescent probes for detecting Al 3+ [14,15]. Naphthalimide derivatives have excellent photochemical and physical properties, which makes them become hot spots in fluorescence probes for detecting ions.…”