Nanowire Chemical/Biological Sensors: Status and a Roadmap for the Future

Fennell, John F.; Liu, Sophie F.; Azzarelli, Joseph M.; Weis, Johannes; Rochat, Sébastien; Mirica, Katherine A.; Ravnsbæk, Jens B.; Swager, Timothy M.

doi:10.1002/anie.201505308

Cited by 243 publications

(184 citation statements)

References 253 publications

Supporting

Mentioning

182

Contrasting

Unclassified

Order By: Relevance

“…It is the property by which a gas sensor can accurately detect the presence of a specific gas in the presence of other interferents. Although absolute selectivity may be difficult to achieve, relative selectivity is highly possible if selectivity is defined contextually, that is, previous knowledge of known interferents in a targeted application or environment ( 25 ). …”

Section: Resultsmentioning

confidence: 99%

Room temperature multiplexed gas sensing using chemical-sensitive 3.5-nm-thin silicon transistors

et al. 2017

View full text Add to dashboard Cite

show abstract

Section: Resultsmentioning

confidence: 99%

Room temperature multiplexed gas sensing using chemical-sensitive 3.5-nm-thin silicon transistors

et al. 2017

View full text Add to dashboard Cite

show abstract

“…Single-walled carbon nanotube (SWCNT) chemiresistors and chemical field effect transistors (Chem-FET) have been shown to provide suitable platforms for the detection of various gases. [10][11][12][13][14][15] Random networks of functionalized SWCNTs have produced sensors that are inexpensive to fabricate, operate at room temperature, and have ultra-low power requirements. [16,17] Theoretical and experimental reports have suggested that CO does not engage in charge transfer with pristine SWCNTs, [18][19][20] indicating the a chemical reactive interface is necessary.…”

mentioning

confidence: 99%

Bio‐Inspired Carbon Monoxide Sensors with Voltage‐Activated Sensitivity

Savagatrup

Schroeder

et al. 2017

Angewandte Chemie

Self Cite

View full text Add to dashboard Cite

Correspondence to: Timothy M. Swager. + These authors contributed equally to this work.Supporting information and the ORCID identification number(s) for the author(s) of this article can be found under: https://doi.org/ 10.1002/anie.201707491. Conflict of interestThe authors declare the following competing financial interest(s): A patent has been filed on this technology. HHS Public Access Author Manuscript Author ManuscriptAuthor Manuscript Author ManuscriptCarbon monoxide (CO) outcompetes oxygen when binding to the iron center of hemeproteins, leading to a reduction in blood oxygen level and acute poisoning. Harvesting the strong specific interaction between CO and the iron porphyrin provides a highly selective and customizable sensor. We report the development of chemiresistive sensors with voltage-activated sensitivity for the detection of CO comprising iron porphyrin and functionalized single-walled carbon nanotubes (F-SWCNTs). Modulation of the gate voltage offers a predicted extra dimension for sensing. Specifically, the sensors show significant increase in sensitivity toward CO when negative gate voltage is applied. The dosimetric sensors are selective to ppm levels of CO and functional in air. UV/Vis spectroscopy, differential pulse voltammetry, and density functional theory reveal that the in situ reduction of Fe III to Fe II enhances the interaction between the F-SWCNTs and CO. Our results illustrate a new mode of sensors wherein redox active recognition units are voltageactivated to give enhanced and highly specific responses. CommunicationsRevving up for sensing: A platform for voltage-activated, chemiresistive gas detection has been delveloped based on covalently functionalized single-walled carbon nanotubes decorated with voltage-responsive chemical selectors. The sensor is highly selective towards CO in the presence of oxygen, nitrogen, and carbon dioxide and is robust to humidity and remains operational in air. KeywordsCarbon monoxide; carbon nanotubes; iron porphyrin; sensors; voltage-activated Carbon monoxide (CO) is responsible for more than half of all fatal poisoning worldwide. [1] Exposure to the colorless, tasteless, and odorless gas is difficult to discern as the initial symptoms of poisoning (headache, dizziness, and confusion) are nonspecific. In the United States, the Occupational Safety and Health Administration (OSHA) has designated permissible exposure limits of 50 ppm over eight hours and 200 ppm over five minutes. [2] The affinity of iron porphyrin towards CO is well-documented for the enzymes cytochrome P450, [3][4][5] hemoglobin, [6] and myoglobin. [7] This high affinity for CO over O 2 of hemoglobin and myoglobin is the underlying mechanism of carbon monoxide poisoning in mammals. [8,9] Although detectors for CO are available, there remains a need for massively [16,17] Theoretical and experimental reports have suggested that CO does not engage in charge transfer with pristine SWCNTs, [18][19][20] indicating the a chemical reactive interface is necessary. Conductivity...

show abstract

“…Moreover, the functionalization of the peptides via genetic engineering could be harnessed to add chemical tags for the selective and specific integration of the nanowires into electronic devices. The ability to design and mass‐produce generations of protein nanowires using recombinant peptides as building blocks and their assembly in a cell‐free environment contrasts with the harsh protocols and specialized equipment that is traditionally needed to fabricate inorganic nanowires (Long et al ., 2012) and the challenges that still remain for their functionalization (Cui et al ., 2001; Fennell et al ., 2016). Conductive peptides and protein nanowires also circumvent major concerns about the toxicity of many conductive nanomaterials, which could facilitate their commercial implementation (Love et al ., 2012).…”

Section: Discussionmentioning

confidence: 99%

Harnessing the power of microbial nanowires

Reguera

2018

Microbial Biotechnology

View full text Add to dashboard Cite

SummaryThe reduction of iron oxide minerals and uranium in model metal reducers in the genus Geobacter is mediated by conductive pili composed primarily of a structurally divergent pilin peptide that is otherwise recognized, processed and assembled in the inner membrane by a conserved Type IVa pilus apparatus. Electronic coupling among the peptides is promoted upon assembly, allowing the discharge of respiratory electrons at rates that greatly exceed the rates of cellular respiration. Harnessing the unique properties of these conductive appendages and their peptide building blocks in metal bioremediation will require understanding of how the pilins assemble to form a protein nanowire with specialized sites for metal immobilization. Also important are insights into how cells assemble the pili to make an electroactive matrix and grow on electrodes as biofilms that harvest electrical currents from the oxidation of waste organic substrates. Genetic engineering shows promise to modulate the properties of the peptide building blocks, protein nanowires and current‐harvesting biofilms for various applications. This minireview discusses what is known about the pilus material properties and reactions they catalyse and how this information can be harnessed in nanotechnology, bioremediation and bioenergy applications.

show abstract

Nanowire Chemical/Biological Sensors: Status and a Roadmap for the Future

Cited by 243 publications

References 253 publications

Room temperature multiplexed gas sensing using chemical-sensitive 3.5-nm-thin silicon transistors

Room temperature multiplexed gas sensing using chemical-sensitive 3.5-nm-thin silicon transistors

Bio‐Inspired Carbon Monoxide Sensors with Voltage‐Activated Sensitivity

Harnessing the power of microbial nanowires

Contact Info

Product

Resources

About