Nanotoxicology and Challenges of Translation

PourGashtasbi, Ghazal

doi:10.2217/nnm.15.131

Cited by 9 publications

(2 citation statements)

References 40 publications

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“…Nanomedical research asks for novel forms of assessing scientific practices and (nano-)objects involving the demanding process of characterization, questions concerning biodistribution, half-life prolongation, circulation time of novel drugs, controllability and sustainability of drug release, levels of intercellular concentration of nanodrugs and so on [46].The limits of taken for granted strategies, practices and technologies in the laboratory also includes for instance the questionability of highly taken for granted models in achieving valid results. So, for example, the production and use of model organisms (animal models) became a source of uncertainty and dispute in the process of accomplishing reliable results for research into human health issues [47,48].…”

Section: The Culture Of Promise and Nanomedical Researchmentioning

confidence: 99%

Caring for Social Complexity in Nanomedicine

Schillmeier¹

2015

Nanomedicine (Lond.)

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In this paper, I will discuss from a 'Science and Technology Studies' perspective three different modes of caring about the social complexity in biomedical and nanomedical research. Nanomedical research unfolds a variety of issues that generate different concerns, questions, problems, requirements and interests that connect with different systems of action (in vitro, in vivo), different kinds (human, nonhuman) and different scales of action (nano, micro, macro). To adequately address the social complexity, I will discuss three possible modes of caring about social complexity: laboratory experiment and scientific analysis, public expert controversies, and publics. These different modes of caring share an experimental ethos that engages nanomedical issues for which no common solutions are available.

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Section: The Culture Of Promise and Nanomedical Researchmentioning

confidence: 99%

Caring for Social Complexity in Nanomedicine

Schillmeier¹

2015

Nanomedicine (Lond.)

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“…This problem is inherent in nanotechnology in general [ 217 ]. The fact that the problem is broader and very urgent is indicated by the introduction of the terms “crisis of translation” [ 218 ], reproducibility crisis [ 219 , 220 ], and other similar phrases expressing concern about the slow progress in this area, into scientific circulation.…”

Section: Problems Of Medical Application Of Magnetic Nanoparticlesmentioning

confidence: 99%

Magnetic Nanoparticles in Medicine: Progress, Problems, and Advances

Koksharov

Губин

Taranov

et al. 2022

J. Commun. Technol. Electron.

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The review presents an analysis of the current state of research related to the design, development, and practical application of methods for biomedical radioelectronics and nanomedicine, including the use of magnetic nanoparticles. The important role of rational scientific physical approaches and experimental methods in the design of efficient and safe magnetic nanoparticle-based agents for therapy, controlled targeted drug delivery, and diagnostics, including spatial imaging, is emphasized. Examples of successful practical application of magnetic nanoparticles in medicine based on these methods are given, and an analysis of the main problems and prospects of this area of science is conducted.

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