“…The deficiency of this metal can be caused many problems in the human body such as anemia, hair loss, increased blood cholesterol, and immunodeficiency [6][7][8][9]. Importantly, this element has been widely deployed as catalyst in organic reactions for the synthesis of heterocycle, medicinal and natural compounds via assorted methods [10][11][12][13][14][15][16][17][18][19][20][21][22][23]. The advantageous methods for determining copper ions in various samples comprise electrochemical methods such as voltammetry, colorimetric, potentiometric chromatography, atomic adsorption (AAs), techniques inductively coupled plasma (ICP), UV-Vis, and photoluminescence techniques (among them, optical methods are excellent means for measuring the copper ions due to their high selectivity, sensitivity, inexpensive nature, and a wide linear range) [24][25][26][27][28][29][30][31][32][33][34][35][36].…”