Nanotechnology and medicine

Emerich, Dwaine F.; Thanos, Christopher G.

doi:10.1517/14712598.3.4.655

Cited by 385 publications

(102 citation statements)

References 52 publications

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“…One iteration of this technology uses quantum dot nanocrystals (e.g. colloidal inorganic semiconductor nanocrystals consisting of a CdSe core and a ZnS shell) that are several nanometers in diameter and manufacturable in a nearly unlimited range of sharply defined colors [241]. Aside from the clinical potential of these particles, their research value includes the possibility of simultaneously tagging multiple biomolecules both on and inside cells to monitor the complex cellular changes and events associated with disease, providing valuable clues for the development of future pharmaceuticals and therapeutics.…”

Section: Nervous System Nanodrugsmentioning

confidence: 99%

Revolutionary Impact of Nanodrug Delivery on Neuroscience

Khanbabaie

Jahanshahi

2012

Current Neuropharmacology

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Brain research is the most expanding interdisciplinary research that is using the state of the art techniques to overcome limitations in order to conduct more accurate and effective experiments. Drug delivery to the target site in the central nervous system (CNS) is one of the most difficult steps in neuroscience researches and therapies. Taking advantage of the nanoscale structure of neural cells (both neurons and glia); nanodrug delivery (second generation of biotechnological products) has a potential revolutionary impact into the basic understanding, visualization and therapeutic applications of neuroscience. Current review article firstly provides an overview of preparation and characterization, purification and separation, loading and delivering of nanodrugs. Different types of nanoparticle bioproducts and a number of methods for their fabrication and delivery systems including (carbon) nanotubes are explained. In the second part, neuroscience and nervous system drugs are deeply investigated. Different mechanisms in which nanoparticles enhance the uptake and clearance of molecules form cerebrospinal fluid (CSF) are discussed. The focus is on nanodrugs that are being used or have potential to improve neural researches, diagnosis and therapy of neurodegenerative disorders.

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Section: Nervous System Nanodrugsmentioning

confidence: 99%

Revolutionary Impact of Nanodrug Delivery on Neuroscience

Khanbabaie

Jahanshahi

2012

Current Neuropharmacology

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“…polycrystalline alumina or hydroxyapatite or partially stabilized zirconia, bioactive glass or glass-ceramics and polyethylenehydroxyapatite composites) have been successfully used for the repair, reconstruction and replacement of diseased or damaged parts of the body, including bone (Roriz et al, 2010). Applications include orthopaedic implants (vertebral prostheses, intervertebral spacers, bone grafting), middle-ear bone replacements and jawbone repair (Chun et al, 2004;Emerich & Thanos, 2003,). For instance, alumina has been used in orthopaedic surgery for more than 20 years as the articulating surface in total hip prostheses because of its exceptionally low coefficient of friction and minimal wear rates.…”

Section: Ceramics In Medicinementioning

confidence: 99%

Synthesis and Thermoluminescent Characterization of Ceramics Materials

Rivera¹

2011

Advances in Ceramics - Synthesis and Characterization, Processing and Specific Applications

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“…Nanotechnology can be defined as the science involved in the design, synthesis, characterisation, and application of materials and devices whose smallest functional organization in at least one dimension is on the nanometer scale 1,2 . It is an emerging field that has contributed to the development of novel diagnostic and therapeutic agents, with the advantage of enhancing drug accumulation at the site of interest and avoiding side effects common to small molecule drugs 3 .…”

Section: Introductionmentioning

confidence: 99%

Nanotechnology in Dentistry

Arruda¹,

Oliveira²,

Paula³

et al. 2017

Arch Health Invest

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Introduction: Nanotechnology is a rapidly expanding field that encompasses the development, manipulation, and application of structures on the nanometer scale. Applications of nanotechnology to dentistry are particularly promising and comprise materials and devices designed to achieve maximal therapeutic efficacy with minimal side effects. Objective: This review discusses the advantages of nanotechnology and the different types of nanostructures used in dentistry. Material and Method: In this study, online databases: pubmed, medline and scielo were searched to analyse the current understanding of the potential of nanotechnology in dentistry, including the restoration of tooth structure with nanocomposites and the development of nanoparticles for dentin remineralisation, drug delivery, disease diagnostics, oral analgesia, oral hygiene maintenance, local anaesthesia, tooth desensitisation, and bone tissue repair. Results: The study demonstrated a wide range of nanotechnological strategies in different dentistry areas and suggests that nanotechnology-based delivery systems may be very useful to improve treatment, prevention and repair in dentistry in the future. Conclusion: There is little or no clinical experience for the nanotechnology-based drug delivery systems cited herein. Safety assessments and clinical trials are the next step in their development.

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Nanotechnology and medicine

Cited by 385 publications

References 52 publications

Revolutionary Impact of Nanodrug Delivery on Neuroscience

Revolutionary Impact of Nanodrug Delivery on Neuroscience

Synthesis and Thermoluminescent Characterization of Ceramics Materials

Nanotechnology in Dentistry

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