Nanotechnology-A New Frontier in Medical Microbiology

Somavarapu, Satyanarayana; Ramesh, B.; Venkatrayulu, Ch.; Chandra, M. Subhosh

doi:10.1007/978-981-15-9916-3_16

Cited by 3 publications

(3 citation statements)

References 78 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Synthetic DNA molecular beacon probes labeled with color codes have been utilized as nano barcodes for the detection of food pathogens. Additionally, silver nanoparticles have been used to coat the surfaces of refrigerators and storage containers to inhibit the spread of foodborne pathogens and food spoilage bacteria [36].…”

Section: Nanoparticles and Quantum Dotsmentioning

confidence: 99%

Multimodal Biosensing of Foodborne Pathogens

Ullah,

Danquah

2023

Preprint

View full text Add to dashboard Cite

Microbial foodborne pathogens can cause major risks to public health and the food industry. Rapid and accurate detection of these pathogens is crucial to prevent outbreaks and ensure food safety. Traditional single-mode biosensing approaches have their limitations in terms of specificity, sensitivity, and speed. Over the years, there has been an increasing research interest in developing multimodal biosensing strategies that integrate multiple sensing techniques to achieve enhanced accuracy, efficacy, and precision in foodborne pathogen detection. This article review paper explores the current state of multimodal biosensing technologies and their promising applications in the food industry. We discuss various integrated biosensing platforms, including optical, electrochemical, and nanomaterial-based systems, among others. The advantages, challenges, and future prospects of multimodal biosensing for foodborne pathogens are thoroughly examined, highlighting the potential impact of these advanced technologies on food safety and public health.

show abstract

Section: Nanoparticles and Quantum Dotsmentioning

confidence: 99%

Multimodal Biosensing of Foodborne Pathogens

Ullah,

Danquah

2023

Preprint

View full text Add to dashboard Cite

show abstract

“…In addition to these features, they provide real-time decision-making for individualized therapy 22 . Using nanobiosensors, health, and economic sectors benefit from shortened hospital stays, lower treatment costs, and reduced MDR strain infections that cost health systems millions of dollars annually 23,24 . Consequently, biosensor monitoring offers many advantages, and these devices may one day become indispensable equipment, reducing hospital costs for the health system in the future 25 .…”

Section: Introductionmentioning

confidence: 99%

Application of Nanobiosensors in Detection of Pathogenic Bacteria: An Update

Ghafouri,

Kasaei,

Aghili

et al. 2023

Res. Biotechnol. Environ. Sci.

View full text Add to dashboard Cite

Bacterial infections remain a critical public health concern worldwide, necessitating the development of efficient and sensitive diagnostic tools. Nanobiosensors, comprising nanomaterials, offer a novel approach to bacterial pathogen detection. The present review aimed to explore the current research and applications of nanobiosensors for bacterial pathogen detection. Recent discoveries in nanotechnology have facilitated the development of nanobiosensors with remarkable sensitivity and specificity. These nanoscale sensors are designed to detect specific bacterial pathogens through various mechanisms, including aptamers, antibodies, and molecular recognition elements. Furthermore, miniaturization and integration with microfluidic systems have enabled the rapid and point-of-care detection of bacterial infections. Incorporating nanomaterials such as carbon nanotubes, quantum dots, and graphene into biosensing platforms has significantly enhanced their performance, leading to ultrasensitive detection of bacterial antigens and nucleic acids. Additionally, using nanobiosensors with advanced analytical techniques, such as electrochemical, optical, and piezoelectric methods, has expanded the possibilities for accurate and real-time monitoring of bacterial pathogens. Nanobiosensors represent a promising frontier in the battle against bacterial infections. Their exceptional sensitivity, rapid response times, and potential for multiplexed detection make them invaluable tools for the early diagnosis and monitoring of bacterial pathogens. Developing cost-effective and portable nanobiosensors for resource-limited settings becomes increasingly possible as nanotechnology advances.

show abstract

“…The development of novel antibiotics is currently constrained, necessitating an active quest for alternative remedies that could be an alternative to antibiotics. Nanostructures based on noble metals and their compounds stand out as promising candidates for such therapeutics [ 11 , 12 , 13 , 14 , 15 , 16 , 17 ]. These nanoparticles (NPs), with their ability to interact with cells [ 12 , 18 , 19 ], can infiltrate them and disrupt the acid–alkaline balance of bacteria, thereby disturbing their homeostasis [ 12 ].…”

Section: Introductionmentioning

confidence: 99%

Formation Kinetics and Antimicrobial Activity of Silver Nanoparticle Dispersions Based on N-Reacetylated Oligochitosan Solutions for Biomedical Applications

Urodkova,

Uryupina,

Tikhonov

et al. 2023

Pharmaceutics

View full text Add to dashboard Cite

The paper presents the results of the synthesis, a detailed kinetics study, and an investigation of the biological activity of silver nanoparticles (AgNPs) in aqueous solutions of N-reacetylated oligochitosan hydrochloride. UV–visible spectrophotometry and dynamic light scattering were employed to control silver ion reduction. The process was observed to follow a pseudo-first-order law. Transmission and scanning electron microscopy demonstrated that AgNPs ranging in size from 10 to 25 nm formed aggregates measuring 60 to 90 nm, with the aggregate surface coated by a 2–4 nm chitosan shell. X-ray microanalysis and powder X-ray diffractometry were used to study the phase composition, identifying two crystalline phases, nanocrystalline silver and AgCl, present in the dispersions. The antibacterial effect was assessed using the serial dilution method for dispersions with varying degrees of Ag+ conversion. Nanodispersions exhibited significant activity against Escherichia coli, Pseudomonas aeruginosa, Bacillus cereus, and Staphylococcus aureus. Interestingly, the activity did not appear to be heavily influenced by the presence of the AgCl phase or the concentration of Ag+ ions. These synthesized dispersions hold promise for the development of materials tailored for biomedical applications.

show abstract

Nanotechnology-A New Frontier in Medical Microbiology

Cited by 3 publications

References 78 publications

Multimodal Biosensing of Foodborne Pathogens

Multimodal Biosensing of Foodborne Pathogens

Application of Nanobiosensors in Detection of Pathogenic Bacteria: An Update

Formation Kinetics and Antimicrobial Activity of Silver Nanoparticle Dispersions Based on N-Reacetylated Oligochitosan Solutions for Biomedical Applications

Contact Info

Product

Resources

About