Nanotechnological evaluation of protein adsorption on dialysis membrane surface hydrophilized with polyvinylpyrrolidone

Matsuda, Masato; Yamamoto, Kenichiro; Yakushiji, Taiji; Fukuda, Makoto; Miyasaka, Takehiro; Sakai, Kiyotaka

doi:10.1016/j.memsci.2007.10.054

Cited by 40 publications

(28 citation statements)

References 22 publications

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“…Being a nontoxic polymer, soluble in water and organic solvents, PVP is one of the best polymeric additives in ultra- [145,168,169] , macro- [152] , micro-and nanofiltration [160] membrane fabrication, as a pore former and to control the membrane structure, for: biomedical applications (e.g., hemodialysis [147,156,159,165,234,235] ), water purification, wastewater treatment [169,170] , desalination, food processing (e.g., beer and wine filtration), gas separation [149,153,166] , selective permeability, hollow fiber membranes [158,159,173] , and many others. Among the multiple functions that this polymer has in membrane applications, there can be mentioned: it adjusts pore size and pore size distribution [168,171] , antifouling properties [168,172] , good compatibility with a broad variety of compounds, ability to form hydrophilic membrane by crosslinking, increases membrane permeability, strong polar character and hydrophilicity improves selective material separation properties, high biocompatibility, especially with blood, and toxicologically safe.…”

Section: Membranesmentioning

confidence: 99%

“…Among the multiple functions that this polymer has in membrane applications, there can be mentioned: it adjusts pore size and pore size distribution [168,171] , antifouling properties [168,172] , good compatibility with a broad variety of compounds, ability to form hydrophilic membrane by crosslinking, increases membrane permeability, strong polar character and hydrophilicity improves selective material separation properties, high biocompatibility, especially with blood, and toxicologically safe. The main uses are in polysulfone (PS) [146,156,157,169,172,234,235] , polyethersulfone (PES) [145,147,154,158,167] , polyphenylene oxide (PPO) [153] and polyvinylidene fluoride (PVDF) membranes.…”

Section: Membranesmentioning

confidence: 99%

“…PVP is used as a hydrophilizing agent in dialysis membranes to inhibit the excessive adsorption of blood proteins [147,156] . It is required that the membrane inner surface to present a uniform hydrophilicity-hydrophobicity distribution and studies conducted by Yamazaki et al showed that the addition of PVP is favorable in this regard [165] .…”

Section: Membranesmentioning

confidence: 99%

“…In this regard, some investigations can be mentioned: a) Electronic and optical applications: nanofibers with fluorescent and magnetic properties [91,107] , nanofibers with high thermal conductivities [133] , nanofibers for energy storage devices [123,138] , nanofibers as sensitive layers in Love-wave gas sensor devices [211] , ultrafine photoluminescent fibers [109] , hollow fibers for microfluids, photonics, and energy storage [173] ; b) Biomedical applications: nanofibers for wounds and burns dressing [97,102,216] , nanofibers for fast-dissolving drug delivery membranes [163] , drug containing nanofibers [96,208] , superhydrophobic core-shell nanofibers for wound healing [103] , magnetic core-shell composite nanoparticles incorporated in PVP fibers for cellular imaging, hollow fiber dialysis membrane [156,159] , drug delivery and nanosensing [91] , and others [11,97,107] ; c) Other types of nanofibers [138,173,184] , nanofibers for water-soluble filters [166] , alumina fibers with PVP as spinning additive for fiber reinforcement of metals, ceramics and resins [186] .…”

Section: Fiber and Textilesmentioning

confidence: 99%

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Poly(vinylpyrrolidone) – A Versatile Polymer for Biomedical and Beyond Medical Applications

Teodorescu¹,

Bercea²

2015

Polymer-Plastics Technology and Engineering

373

222

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The high versatility of poly(vinylpyrrolidone) (PVP) can be explained by its diverse properties including its solubility in water and in a broad range of liquid media, high chemical and thermal resistance, and unique wetting, binding, and film-forming properties. Thanks to biocompatibility, absence of toxicity and high capacity to form interpolymer complexes, PVP is widely used for designing materials for different applications, such as biomaterials for medical and nonmedical uses. This review summarizes a vast diversity of applicative examples showing the tremendous opportunities for future research and developments of PVP based biomaterials.

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Section: Membranesmentioning

confidence: 99%

Section: Membranesmentioning

confidence: 99%

Section: Membranesmentioning

confidence: 99%

Section: Fiber and Textilesmentioning

confidence: 99%

See 2 more Smart Citations

Poly(vinylpyrrolidone) – A Versatile Polymer for Biomedical and Beyond Medical Applications

Teodorescu¹,

Bercea²

2015

Polymer-Plastics Technology and Engineering

373

222

View full text Add to dashboard Cite

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“…We have clarified the biocompatibility and nanoscale surface properties of PSf/PVP films containing different amounts of PVP [5,6]. Increasing the PVP content enhances the surface hydrophilicity.…”

Section: Introductionmentioning

confidence: 97%

Poly(N-vinyl-2-pyrrolidone) elution from polysulfone dialysis membranes by varying solvent and wall shear stress

et al. 2012

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Some dialysis patients are treated with post-hemodiafiltration (HDF); the blood viscosity of the patients who undergo post-HDF is higher than that of the patients who undergo conventional hemodialysis. This study aims to evaluate poly(N-vinyl-2-pyrrolidone) (PVP) elution from PSf dialysis membranes by varying solvents and high wall shear stress caused by blood viscosity. We tested three commercial membranes: APS-15SA (Asahi Kasei Kuraray), CX-1.6U (Toray) and FX140 (Fresenius). Dialysate and blood sides of the dialyzers were primed with reverse osmosis (RO) water and saline. RO water, saline and dextran solution (2.9 and 5.8 mPa s) were circulated in the blood side. The amount of eluted PVP was determined by 0.02 N iodometry. The hardness and adsorption force of human serum albumin (HSA) on the membrane surfaces were measured by the atomic force microscope. When wall shear stress was increased using dextran, the amount of PVP eluted by the 2.9 mPa s solution equaled that eluted by the 5.8 mPa s solution with APS-15SA and CX-1.6U sterilized by gamma rays. The amount of PVP eluted by the 5.8 mPa s solution was higher than that eluted by the 2.9 mPa s solution with FX140 sterilized by autoclaving. The wall shear stress increased the PVP elution from the surface, hardness and adsorption force of HSA. Sufficient gamma-ray irradiation is effective in decreasing PVP elution.

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Atomic Force Microscopy, Transmission Electron Microscopy, Scanning Electron Microscopy, and FourierTransform‐InfraredSpectroscopic Imaging as Tools to Study Various Phenomena Involving Poly(Vinylpyrrolidone)

McMullen

2021

Handbook of Pyrrolidone and Caprolactam Based Materials

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This chapter examine state‐of‐the‐art advanced imaging techniques and how these tools can be used to study polymer blends and composites containing poly(vinylpyrrolidone) (PVP) and its derivatives. The imaging technologies discussed consist of many of the modes of atomic force microscopy as well as basic and advanced methods in transmission electron microscopy (TEM) and scanning electron microscopy (SEM). There are two principal types of electron microscopy, SEM and TEM. Both techniques provide different types of information about the sample under investigation. The chapter demonstrates the use of Fourier transform–infrared (FT‐IR) spectroscopic imaging to spatially map elements of multicomponent systems. FT‐IR spectroscopic imaging is a technique that involves the coupling of an FT‐IR spectrometer with an optical microscope. Powerful tool based on AFM and IR spectroscopy has become available to researchers. The chapter also demonstrates the use of imaging technologies to characterize PVP‐metal nanoparticle composites with a specific focus on silver and gold particles.

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Nanotechnological evaluation of protein adsorption on dialysis membrane surface hydrophilized with polyvinylpyrrolidone

Cited by 40 publications

References 22 publications

Poly(vinylpyrrolidone) – A Versatile Polymer for Biomedical and Beyond Medical Applications

Poly(vinylpyrrolidone) – A Versatile Polymer for Biomedical and Beyond Medical Applications

Poly(N-vinyl-2-pyrrolidone) elution from polysulfone dialysis membranes by varying solvent and wall shear stress

Atomic Force Microscopy, Transmission Electron Microscopy, Scanning Electron Microscopy, and FourierTransform‐InfraredSpectroscopic Imaging as Tools to Study Various Phenomena Involving Poly(Vinylpyrrolidone)

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