Nanostructured titanium–silver coatings with good antibacterial activity and cytocompatibility fabricated by one-step magnetron sputtering

Bai, Long; Hang, Ruiqiang; Gao, Ang; Zhang, Xiangyu; Huang, Xiaobo; Wang, Yueyue; Tang, Bin; Zhao, Lei; Chu, Paul K.

doi:10.1016/j.apsusc.2015.07.064

Cited by 60 publications

(31 citation statements)

References 45 publications

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“…of stainless steel, commonly obtained when the atmosphere of the sputtering process is composed only of Ar, as has been found by other researchers [9][10][11]. Furthermore, peaks related to the presence of the FCC structure of silver in Ar1Ag and Ar4Ag coatings can be seen [17,21,22]. In the XRD pattern of the target, a face-centred cubic structure with mixed orientation can be seen, where the peaks were indexed as (111), (200) and (220).…”

Section: Resultssupporting

confidence: 67%

A Microstructural and Wear Resistance Study of Stainless Steel-Ag Coatings Produced through Magnetron Sputtering

Recco

Olaya

2018

Coatings

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This paper presents a study of the tribological properties of stainless steel coatings with varying Ag contents, deposited via magnetron sputtering. The growth of the coatings was done in Ar and Ar + N2 atmospheres in order to change the crystalline phase in the coating. The analysis of the chemical composition was performed using energy-dispersive X-ray spectroscopy (EDS) and the structural analysis was performed via X-ray diffraction (XRD). The adhesive wear resistance and the friction coefficient were evaluated using the ball-on-disk test with a ball of alumina. The coatings’ adhesion was measured with a scratch tester and the mechanical properties were evaluated with a nanoindenter. The morphology of the films and the wear track were characterized via scanning electron microscopy (SEM). By means of XRD, phases corresponding to the body-centred cubic (BCC) structure were found for the coatings deposited in an inert atmosphere and face-centred cubic (FCC) for those deposited in a reactive atmosphere. A more compact morphology was observed in coatings with a higher silver content. The values of the hardness increased with an increase in the silver content and the presence of nitrogen in the coatings. In the wear traces, mainly mechanisms of oxidative and adhesive wear and plastic deformation were found. The coefficient of friction decreased with an increase of silver in the coatings, whereas the wear rate decreased.

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Section: Resultssupporting

confidence: 67%

A Microstructural and Wear Resistance Study of Stainless Steel-Ag Coatings Produced through Magnetron Sputtering

Recco

Olaya

2018

Coatings

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“…Compared to pure Ti, the Ti-Ag coatings show good cytocompatibility as indicated by good osteoblast adhesion, proliferation, intracellular total protein synthesis and alkaline phosphatase activity [198]. …”

Section: Synthesis Of Silver Nanoparticles On the Implant Surfacementioning

confidence: 99%

Silver Nanocoating Technology in the Prevention of Prosthetic Joint Infection

et al. 2016

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Prosthetic joint infection (PJI) is a feared complication of total joint arthroplasty associated with increased morbidity and mortality. There is a growing body of evidence that bacterial colonization and biofilm formation are critical pathogenic events in PJI. Thus, the choice of biomaterials for implanted prostheses and their surface modifications may significantly influence the development of PJI. Currently, silver nanoparticle (AgNP) technology is receiving much interest in the field of orthopaedics for its antimicrobial properties and a strong anti-biofilm potential. The great advantage of AgNP surface modification is a minimal release of active substances into the surrounding tissue and a long period of effectiveness. As a result, a controlled release of AgNPs could ensure antibacterial protection throughout the life of the implant. Moreover, the antibacterial effect of AgNPs may be strengthened in combination with conventional antibiotics and other antimicrobial agents. Here, our main attention is devoted to general guidelines for the design of antibacterial biomaterials protected by AgNPs, its benefits, side effects and future perspectives in PJI prevention.

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“…The desired antibacterial ability can be obtained only by the choice of the optimal processing parameters. Bai et al [108] have fabricated Ti-Ag composite coatings with different Ag contents (1.2-21.6 at %) using co-sputtering Ti-Ag targets by MS. The composite coating showed long-term antibacterial ability.…”

Section: Mao Assisted By Msmentioning

confidence: 99%

Review of Antibacterial Activity of Titanium-Based Implants’ Surfaces Fabricated by Micro-Arc Oxidation

Zhang

Wang

et al. 2017

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Ti and its alloys are the most commonly-used materials for biomedical applications. However, bacterial infection after implant placement is still one of the significant rising complications. Therefore, the application of the antimicrobial agents into implant surfaces to prevent implant-associated infection has attracted much attention. Scientific papers have shown that inorganic antibacterial metal elements (e.g., Ag, Cu, Zn) can be introduced into implant surfaces with the addition of metal nanoparticles or metallic compounds into an electrolyte via micro-arc oxidation (MAO) technology. In this review, the effects of the composition and concentration of electrolyte and process parameters (e.g., voltage, current density, oxidation time) on the morphological characteristics (e.g., surface morphology, bonding strength), antibacterial ability and biocompatibility of MAO antimicrobial coatings are discussed in detail. Anti-infection and osseointegration can be simultaneously accomplished with the selection of the proper antibacterial elements and operating parameters. Besides, MAO assisted by magnetron sputtering (MS) to endow Ti-based implant materials with superior antibacterial ability and biocompatibility is also discussed. Finally, the development trend of MAO technology in the future is forecasted.

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Nanostructured titanium–silver coatings with good antibacterial activity and cytocompatibility fabricated by one-step magnetron sputtering

Cited by 60 publications

References 45 publications

A Microstructural and Wear Resistance Study of Stainless Steel-Ag Coatings Produced through Magnetron Sputtering

A Microstructural and Wear Resistance Study of Stainless Steel-Ag Coatings Produced through Magnetron Sputtering

Silver Nanocoating Technology in the Prevention of Prosthetic Joint Infection

Review of Antibacterial Activity of Titanium-Based Implants’ Surfaces Fabricated by Micro-Arc Oxidation

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