Nanostructured ceramics in medical devices: Applications and prospects

Narayan, Roger J.; Kumta, Prashant N.; Sfeir, Charles; Lee, Dong-Hyun; Choi, Daiwon; Olton, Dana

doi:10.1007/s11837-004-0289-x

Cited by 82 publications

(57 citation statements)

References 66 publications

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“…Following this definition, in the past 25 years nanotechnology has expanded from Feynman's idea and now finds applications in fields ranging from medical devices to nano-reinforced concrete [3,4].…”

Section: Nanotechnology In Concretementioning

confidence: 99%

“…Li et al confirmed that the flexural and compressive strength of the concrete was enhanced, but they did not study the electrical properties. The same group later studied the electrical volume resistivity of cement paste containing CNT measured using the four-probe method [39]. They applied a cyclic compressive load to a 40.0 mm by 40.0 mm by 160.0 mm (1.575 in.…”

Section: Carbon Fiber Cement and Mortar Self-sensing Applicationsmentioning

confidence: 99%

“…It was discovered by Gao et al that CNF has an optimal dosage of approximately 1% by volume [12] [12]. It was found by many researchers that increased steel fiber increases concrete properties; however, after a percentage of 1% fibers by volume, the concrete becomes increasingly less workable, which could cause problems in construction such as honeycombing [39][40][41]. The main goal of testing the SCCNFC column was to prove that concrete containing CNF can be used as a sensor.…”

Section: Damage Detection Of Cnf Concrete Columnsmentioning

confidence: 99%

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2013

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Section: Nanotechnology In Concretementioning

confidence: 99%

Section: Carbon Fiber Cement and Mortar Self-sensing Applicationsmentioning

confidence: 99%

Section: Damage Detection Of Cnf Concrete Columnsmentioning

confidence: 99%

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Carbon Nanofiber Concrete for Damage Detection of Infrastructure

Mo¹,

Roberts²

2013

Advances in Nanofibers

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“…Hydroxyapatite is the most ubiquitous and well-known phase of calcium phosphate. It has the Ca/P ratio of 1.67 (Narayan et al, 2004). Different phases of calcium phosphate ceramics are used depending upon whether a resorbable or bioactive material is desired.…”

Section: Calcium Phosphates Familymentioning

confidence: 99%

Nano-Particulate Calcium Phosphate as a Gene Delivery System

Mostaghaci¹,

Hanifi²,

Loretz³

et al. 2011

Non-Viral Gene Therapy

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“…Mechanical deformation theory indicates that as grain size is reduced, high-volume fractions of interfacial regions compared with bulk leads to increased deformation by grain-boundary sliding and short-range diffusion-healing events, thus, increased ductility in nanocrystalline ceramics may be observed. 17,18 Indeed, greater mechanical properties have been reported for polymer composites with a reduction in ceramic grain size into the nanometer range. 19 For example, McManus et al reported that the bending moduli of composites of PLA with 40 and 50 wt% nanophase (,100 nm) alumina, titania and HA were significantly greater than respective composite formulations with conventional coarser grained ceramics.…”

Section: Introductionmentioning

confidence: 99%

Mechanical properties of dispersed ceramic nanoparticles in polymer composites for orthopedic applications

Liu

Webster²

2010

IJN

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Ceramic/polymer composites have been considered as third-generation orthopedic biomaterials due to their ability to closely match properties (such as surface, chemistry, biological, and mechanical) of natural bone. It has already been shown that the addition of nanophase compared with conventional (or micron-scale) ceramics to polymers enhances bone cell functions. However, in order to fully take advantage of the promising nanometer size effects that nanoceramics can provide when added to polymers, it is critical to uniformly disperse them in a polymer matrix. This is critical since ceramic nanoparticles inherently have a strong tendency to form larger agglomerates in a polymer matrix which may compromise their properties. Therefore, in this study, model ceramic nanoparticles, specifically titania and hydroxyapatite (HA), were dispersed in a model polymer (PLGA, poly-lactic-co-glycolic acid) using high-power ultrasonic energy. The mechanical properties of the resulting PLGA composites with well-dispersed ceramic (either titania or HA) nanoparticles were investigated and compared with composites with agglomerated ceramic nanoparticles. Results demonstrated that well-dispersed ceramic nanoparticles (titania or HA) in PLGA improved mechanical properties compared with agglomerated ceramic nanoparticles even though the weight percentage of the ceramics was the same. Specifically, well-dispersed nanoceramics in PLGA enhanced the tensile modulus, tensile strength at yield, ultimate tensile strength, and compressive modulus compared with the more agglomerated nanoceramics in PLGA. In summary, supplemented by previous studies that demonstrated greater osteoblast (bone-forming cell) functions on well-dispersed nanophase ceramics in polymers, the present study demonstrated that the combination of PLGA with well-dispersed nanoceramics enhanced mechanical properties necessary for load-bearing orthopedic/dental applications.

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Nanostructured ceramics in medical devices: Applications and prospects

Cited by 82 publications

References 66 publications

Carbon Nanofiber Concrete for Damage Detection of Infrastructure

Carbon Nanofiber Concrete for Damage Detection of Infrastructure

Nano-Particulate Calcium Phosphate as a Gene Delivery System

Mechanical properties of dispersed ceramic nanoparticles in polymer composites for orthopedic applications

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