Nanosized iron and iron oxide powders promising for medicine

Abstract

3 UDC 620.193.8Nanosized iron-based powders of different compositions and particle sizes have been developed for medical application. It is shown that their structural and phase compositions, which are related to their magnetic properties, can be controlled. The interaction of the powders with model media such as human blood plasma and its mixture with 0.9% NaCl solution (1 : 1), distilled water, and 0.9% NaCl solution is studied. The rate of powder dissolution in blood plasma is established to depend on the α-iron content and particle size: the higher these parameters, the more intensive the powder biotransformation. The Fe 3 O 4 powders are quite resistant to model biomedia: their solubility in media containing blood plasma is one-hundredth to seven-thousandths of α-Fe solubility.

Solution Combustion Synthesis and Characterization of Magnetite, Fe3O4, Nanopowders

“…Magnetite, Fe 3 O 4 , has attracted considerable interest because of its remarkable properties, which recommend it for a wide field of applications, such as: ferrofluids, magnetic hyperthermia, magnetic resonance imaging, magnetic drug delivery, catalyst, magnetic storage media, removal of different contaminants from water, etc . At the same time, the production of pure Fe 3 O 4 powders with appropriate features (large surface area, small particle size, narrow size distribution, good magnetic properties etc.)…”

Influence of silver content on rifampicin adsorptivity for magnetite/Ag/rifampicin nanoparticles

“…The preparation procedure of magnetite/Ag/rifampicin NPs included three stages: synthesis of magnetite nanopowder, silver deposition and rifampicin attachment. Magnetite nanopowder was synthesized by thermochemical technique [22] which is based on thermal decomposition and reduction of iron oxalate in a special gaseous atmosphere (450 °C-470 °C, 2 h).…”