Nanoscale battery cathode materials induce DNA damage in bacteria

Abstract

The increasing use of nanoscale lithium nickel manganese cobalt oxide (LixNiyMnzCo1-y-zO2, NMC) as a cathode material in lithium-ion batteries poses risk to the environment. Learning toxicity mechanisms on molecular levels...

Transformations and Environmental Impacts of Copper Zinc Tin Sulfide Nanoparticles and Thin Films

“…The observed toxicity could be due to several factors such as dissolved ions, disruption of cell surface structures, DNA damage, or ROS generation based on NP transformation. The observation of increasing toxicity over time due to gradual ion dissolution has been reported in other nanomaterial studies such as those with lithiated nickel manganese cobalt oxide and Ag NPs − and thus was considered a likely culprit here. While we cannot directly calculate the concentration at which 50% of bacteria are killed in this experiment (or LC 50 value), Figure suggests that it likely lies between 50 and 100 mg/L of CZTS.…”

Comparable antibacterial effects and action mechanisms of ethyl cyanoacrylate nanoparticles on Bacillus subtilis and Escherichia coli evaluated by transcriptome and morphological changes

“…Reports have shown diverse changes in the cellular processes that are specific on the tested strains. 37,38…”

Chronic exposure to complex metal oxide nanomaterials induces production of reactive oxygen species in bacteria

“…Reports suggest that in addition to being toxic, NMC decreases cellular respiration in bacteria, as measured by oxygen consumption and also leads to DNA damage within eight hours of exposure in S. oneidensis, as studied by the Comet assay and high-resolution DNA adductomics. 10,13 Interestingly, NMC nanoparticles cannot enter the bacteria as determined by high resolution scanning electron microscopy and transmission electron microscopy and are believed to exert toxic effects by their presence in the vicinity of the cells. 10 NMC is transformed in liquid as shown by surface composition studies using XPS and metal dissolution by ICP-OES.…”

“…Ultimately, widespread damage can result, such as protein and lipid damage, disruption of metal homeostasis, DNA strand breakage, and single nucleotide modifications. 13,14,[35][36][37] The present study examines the roles of ROS in the response of S. oneidensis to NMC with focus on filamentation, DNA damage, and mutation.…”