Nanoparticulate Drug Delivery System: A Novel Approach

Ashara, Kalpesh Chhotalal; Paun, Jalpa S.; Soniwala, Moinuddin; Chavada, J. R.; Badjatiya, J. K.

doi:10.22270/ijdra.v1i2.109

Cited by 3 publications

(2 citation statements)

References 4 publications

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“…Thermo sensitive niosomes were set up by Raja Naresh et al by evaporating the organic solvent at 60°C and leaving a thin film of lipid on the wall of rotary flash evaporator. The aqueous stage containing drug was included gradually with intermittent shaking of flask at room temperature took after by sonication [7,8] (Figure 3).…”

Section: B] Hand Shaking Methods (Thin Film Hydration Technique)mentioning

confidence: 99%

Niosomes : Novel Drug Delivery Systems

2024

IJFMR

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The administration of medications to specific targets with minimal affinity to other organs is a challenge during the treatment of disease conditions. Novel drug delivery systems enable localization of drugs to their site of action. These targeted drug delivery systems use various carriers, such as serum proteins, liposomes, synthetic polymers, and microspheres. Niosomes are a type of drug delivery system that has a bilayer structure made of non-ionic surfactants. Niosomes are amphiphilic; hence, they can encapsulate both lipophilic and lipophobic drugs and increase their bioavailability. Current work describes the structure, various methods of preparation and applications of niosomes.

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Section: B] Hand Shaking Methods (Thin Film Hydration Technique)mentioning

confidence: 99%

Niosomes : Novel Drug Delivery Systems

2024

IJFMR

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“…They can overcome drug instability, solubility, and rapid degradation due to their properties, which include decreased toxicity, enhanced drug bioavailability and presence in the systemic circulation, and maintained drug release. Vesicular systems enhance patient adherence and efficacy by achieving the long-term therapeutic potential that is highly controlled [ 10 , 140 , 141 ]. There are diverse types of vesicular systems used in the delivery of antimalarial drugs, such as liposomes, ethosomes, and niosomes.…”

Section: Nanodrug Delivery Systemsmentioning

confidence: 99%

Current advances in nanodrug delivery systems for malaria prevention and treatment

Kekani

Witika

2023

Discover Nano

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Malaria is a life-threatening, blood-borne disease with over two hundred million cases throughout the world and is more prevalent in Sub-Saharan Africa than anywhere else in the world. Over the years, several treatment agents have been developed for malaria; however, most of these active pharmaceutical ingredients exhibit poor aqueous solubility and low bioavailability and may result in drug-resistant parasites, thus increasing malaria cases and eventually, deaths. Factors such as these in therapeutics have led to a better appreciation of nanomaterials. The ability of nanomaterials to function as drug carriers with a high loading capacity and targeted drug delivery, good biocompatibility, and low toxicity renders them an appealing alternative to conventional therapy. Nanomaterials such as dendrimers and liposomes have been demonstrated to be capable of enhancing the efficacy of antimalarial drugs. This review discusses the recent development of nanomaterials and their benefits in drug delivery for the potential treatment of malaria.

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