Nanopartículas e aplicações endodônticas: uma revisão da literatura

Telles, Iris Sol Figueiredo; Prado, Maíra do; Simão, Renata Antoun

doi:10.18363/rbo.v74n2.p.167

Cited by 3 publications

(2 citation statements)

References 38 publications

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“…Após a síntese das nanopartículas é importante realizar a sua caracterização porque, alterações na forma ou tamanho das nanopartículas implicam nas atividades biológicas que desempenharão. Dentre as características físico-químicas relevantes para o estudo das nanopartículas pode citar tamanho, propriedades da superfície, forma, composição, peso molecular, identidade, pureza, estabilidade e solubilidade (Telles, et al, 2017).…”

Section: Metodologiaunclassified

Potencial antimicrobiano das nanopartículas de prata estabilizadas em curcumina e extrato de folhas de cajueiro (Anacardium occidentale L.)

Viana¹,

Viana²,

Figueirêdo³

et al. 2021

RSD

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A pesquisa teve como objetivo analisar o potencial antimicrobiano das nanopartículas de prata estabilizadas em curcumina e extrato de folhas de cajueiro (Anacardium occidentale L). Na metodologia as nanopartículas de prata (AgNPs) foram sintetizadas a partir de 125 mL de nitrato de prata (AgNO3) em ebulição sob agitação magnética e gotejamento de 5 mL de citrato de sódio 1%, e estabilizadas em curcumina e extrato de cajueiro. Os testes antimicrobianos foram realizados contra Staphylococcus aureaus, Escherichia coli, Candida albicans e Pseudomonas aeruginosa. O ensaio consistiu em dispersão do inóculo em toda a superfície das placas e posterior aplicação de discos contendo AgNPs na concentração de 1,0 mmol/L. Os halos formados foram mensurados com auxílio de um paquímetro em milímetros. Os resultados mostram que com as mudanças de coloração da solução na espectroscopia no ultravioleta visível UV-Vis, houve formação de AgNPs e indicaram atividade antimicrobiana contra cepas de Staphylococcus aureus. No entanto, não mostraram atividade inibitória contra a Pseudomonas aeruginosa e a Escherichia coli e também não apresentaram atividade inibitória de crescimento contra o fungo testado. Conclui-se que as AgNPs apresta potencial antimicrobiano contra Staphylococcus aureus. Portanto, devem ser testadas em outros microrganismos com outras concentrações, bem como ser aplicado em outras áreas tecnológicas e da saúde, como na regeneração tecidual.

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Section: Metodologiaunclassified

Potencial antimicrobiano das nanopartículas de prata estabilizadas em curcumina e extrato de folhas de cajueiro (Anacardium occidentale L.)

Viana¹,

Viana²,

Figueirêdo³

et al. 2021

RSD

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“…AgNPs exhibit a broad-spectrum antimicrobial activity against bacteria and fungi [16]. Biogenic AgNPs are a good option among nanoparticles with antimicrobial activities since they present low production cost and good efficacy, stability, and durability [17,18].…”

Section: Introductionmentioning

confidence: 99%

Activity of Fusarium oxysporum-Based Silver Nanoparticles on Candida spp. Oral Isolates

et al. 2022

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Candida spp. resistant to commercially available antifungals are often isolated from patients with oral candidiasis, a situation that points to the need for the development of new therapies. Thus, we evaluated the activity of Fusarium oxysporum-based silver nanoparticles (AgNPs) on Candida spp. isolated from denture stomatitis lesions. Candida isolates were molecularly identified and submitted to susceptibility assays using AgNPs and commercial fungicides. The interference on biofilm formation and the mechanisms of action of AgNPs on Candida spp. were also investigated. Scanning electron microscopy was used to evaluate the morphology of AgNP-treated Candida. Candida albicans was the most frequent species isolated from denture stomatitis cases. All Candida spp. were susceptible to AgNPs at low concentrations, except Candida parapsilosis. AgNPs caused surface damage, cell disruption, and biofilm formation inhibition. The ergosterol supplementation protected C. albicans against the AgNP action. AgNPs are effective against Candida spp. and can be faced as a promising new therapeutic agent against oral candidiasis.

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Evaluation of effectiveness and minimum inhibitory concentration of silver nanoparticles for decontamination of root canal systems

Filho,

Girardello,

Tognetti

et al. 2023

JDHODT

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Endodontics is essential in the process of controlling pain and diseases of the pulp and periapex, thus becoming increasingly innovative, safe and effective. Endodontic treatment has several stages, including the process of canal evolution. This decontamination process is extremely important for the eradication of microorganisms in the SCR and the prevention of reinfection. During the instrumentation it is paramount that constant irrigation occurs to remove inflamed tissues, necrotics and also the biofilm present. The objective of the present study was to analyse the disinfectant capacity of two chemical substances, one of them in different concentrations, o n an aggressive microorganism present in the root canal system. The applied methodology was, in vitro experimental laboratory study, to compare the antimicrobial activity of 1% Sodium Hypochlorite and Silver Nanoparticle at 22 ppm, 70 ppmand 95 ppm, used against the pathogen E. faecalis, which were selected by the bank of microorganisms from the laboratory of Molecular and Clinical Microbiology of the Graduate Program in Health Sciences at Universidade São Francisco (USF), as well as determining the minimum concentration of the silver nanoparticle solution in inhibiting the growth of E. faecalis and P. aeruginosa. Which storage was previously authorized by the Research Ethics Committee of the USF. After data collection, it was possible to conclude from the results that the 1% Sodium Hypochlorite, the Silver Nanoparticle at 70 ppm and 95 ppm, obtained positive results in terms of antimicrobial activity, in comparison with the Silver Nanoparticle at 22 ppm, which obtained a negative result on the microorganism.

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Nanopartículas e aplicações endodônticas: uma revisão da literatura

Cited by 3 publications

References 38 publications

Potencial antimicrobiano das nanopartículas de prata estabilizadas em curcumina e extrato de folhas de cajueiro (Anacardium occidentale L.)

Potencial antimicrobiano das nanopartículas de prata estabilizadas em curcumina e extrato de folhas de cajueiro (Anacardium occidentale L.)

Activity of Fusarium oxysporum-Based Silver Nanoparticles on Candida spp. Oral Isolates

Evaluation of effectiveness and minimum inhibitory concentration of silver nanoparticles for decontamination of root canal systems

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