Nanoparticle–hydrogel superstructures for biomedical applications

Jiang, Yao; Krishnan, Nishta; Heo, Jiyoung; Fang, Ronnie H.; Zhang, Liangfang

doi:10.1016/j.jconrel.2020.05.041

Cited by 126 publications

(96 citation statements)

References 177 publications

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“…In particular, the utility of hydrophobic drugs that are normally difficult to formulate and deliver in vivo can be greatly enhanced with nanotechnology. Therapeutics that are incorporated into nanoparticles can also benefit from a lengthened therapeutic window through sustained release, and these platforms can be further assimilated into hydrogel superstructures for additional capabilities [ 383 ].…”

Section: Discussionmentioning

confidence: 99%

Nanotechnology for virus treatment

et al. 2021

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Section: Discussionmentioning

confidence: 99%

Nanotechnology for virus treatment

et al. 2021

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“…187 Nanocomposite hydrogels are indispensable for biological applications, catalysis and fabricating semiconducting devices. [188][189][190] Based on the same principle, Fe(III)/Fe(II) redox conversion has been utilized extremely in fabricating dynamic gels. For example, Zhang et al synthesized a redox tunable hydrogel system comprising of poly(acrylic acid) (PAAc), hexadecyl methacrylate and Fe(III)-citrate that evolved under UV-light.…”

Section: (Iii) Uv Light Induced Reactionmentioning

confidence: 99%

Stimuli responsive dynamic transformations in supramolecular gels

2021

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“…Nanofibers offer a better choice for skin tissue engineering scaffolds because they are able to imitate the properties of biological tissues (vide infra) [68]. Nanoparticle-hydrogel superstructures, on the other hand, are new materials prepared by embedding nanoparticles in hydrogels to produce nanoplatforms with highly tunable properties and a wide range of applications [69]. In fact, when small quantities of nanosized materials are added to a polymer matrix, the performance of the resultant material is improved to an extraordinary level.…”

Section: Nanohydrogels and Nanoparticle-hydrogel Superstructuresmentioning

confidence: 99%

Nanomaterials in Skin Regeneration and Rejuvenation

Bellu

Medici

Coradduzza

et al. 2021

IJMS

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Skin is the external part of the human body; thus, it is exposed to outer stimuli leading to injuries and damage, due to being the tissue mostly affected by wounds and aging that compromise its protective function. The recent extension of the average lifespan raises the interest in products capable of counteracting skin related health conditions. However, the skin barrier is not easy to permeate and could be influenced by different factors. In the last decades an innovative pharmacotherapeutic approach has been possible thanks to the advent of nanomedicine. Nanodevices can represent an appropriate formulation to enhance the passive penetration, modulate drug solubility and increase the thermodynamic activity of drugs. Here, we summarize the recent nanotechnological approaches to maintain and replace skin homeostasis, with particular attention to nanomaterials applications on wound healing, regeneration and rejuvenation of skin tissue. The different nanomaterials as nanofibers, hydrogels, nanosuspensions, and nanoparticles are described and in particular we highlight their main chemical features that are useful in drug delivery and tissue regeneration.

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Nanoparticle–hydrogel superstructures for biomedical applications

Cited by 126 publications

References 177 publications

Nanotechnology for virus treatment

Nanotechnology for virus treatment

Stimuli responsive dynamic transformations in supramolecular gels

Nanomaterials in Skin Regeneration and Rejuvenation

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