Nanoparticle functionalized laser patterned substrate: an innovative route towards low cost biomimetic platforms

Abstract

Integration of nanotechnology and advanced manufacturing processes presents an attractive route to produce devices for adaptive biomedical device technologies.

Real-time monitoring and control for high-efficiency autonomous laser fabrication of silicon nanoparticle colloids

“…Given that the process recirculates the Nps colloid within the flow-cell, the possibility of photo fragmentation should be considered; however, a trend of size reduction with time was not observed. This observation is in alignment with the hypothesis that minimal photofragmentation of the SiNps should occur under 1064 nm irradiation [19,21] as the absorption Fig. 15 Comparison of at-line and off-line measurements of Np peak diameters up to 30-min ablation time during recirculation mode, including size population width (±2σ), (n = 1) Fig.…”

“…This allows the produced Nps to be functionalized in a single-step either during production, by choice of solution composition [16], or by post-processing [17,18]. Recently, our research group has reported the use of these laser synthesised nanomaterials in biomimetic surfaces [19] and biological sensing applications [20]. The advantage of LASiS over competing techniques is that it allows the targeted, costeffective on-demand production of Nps for research purposes.…”

Advanced Characterisation Techniques for Nanostructures

“…It has attained such market coverage that many nano-colloid researchers rely on it as their sole size characterisation technique. The technique is used for particle analysis in inks, paints, and more recently biological diagnostics and disease treatment systems [40], [41], indeed many fields where nanoparticle size is critical. The technique offers possibilities of in-situ measurement, which can be important for time sensitive process and industrial manufacturing.…”

Taguchi method modelling of Nd:YAG laser ablation of microchannels on cyclic olefin polymer film

“…COC and COP have been reported for use in a wide variety of applications ranging from diffractive optic elements [2], waveguide coatings [3] and as substrates for the deposition of nanomaterial films [4] which exploit the polymer's high transparency in the UV-Visible-NIR range. Furthermore, COPs and COCs have also been exhibits excellent biocompatibility which allows them to find application in high-adhesion biomimetic surfaces [5] and cell culturing platforms [6]. As COP and COC are also noted for low water absorption and resistance to acids, bases and most nonhydrocarbon solvents, they offer an excellent alternative for liquid analysis platforms which have been typically fabricated using PDMS and PMMA to-date.…”

“…Primary ANOVA parameters for the four Taguchi models. ZF16 = (0.05 − 1.60 × 10 −4 d − 0.02 + 0.04 − 0.01 + 2.01 × −4 − 0.04 + 0.01 ) −1(6) …”