Nanomaterials in consumer's goods: the problems of risk assessment

Gmoshinski, I. V.; Хотимченко, С А

doi:10.1088/1757-899x/98/1/012009

Cited by 3 publications

(2 citation statements)

References 52 publications

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“…There is a wide variety of nanomaterials, however, the main applications are by means of simple nanoparticles, nanoemulsion, liposome, nanostructured lipid carrier, multilayer nanoparticles, agglomerated nanoparticles, nanofilms, and nanocomposites [41]. There are five areas where studies and development in the field of food are focused [42][43][44][45][46][47][48][49][50][51][52][53][54][55][56][57][58][59][60], as seen in Figure 14.…”

Section: Figure 13 Dimension Comparisonmentioning

confidence: 99%

High-Intensity Ultrasound and Its Interaction with Foodstuff and Nanomaterials

Rentería‐Monterrubio¹,

Chávez‐Martínez²,

Juárez-Moya³

et al. 2022

Trends and Innovations in Food Science

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In recent decades, food research has focused on hybrid systems, that is, the application of nanomaterials and the so-called emerging technologies, whose objective is to increase the quality of food. Among these technologies that are different from thermal is high intensity ultrasound. This chapter presents and describes the interaction of acoustic waves supported by classical physics and nanomaterials generated by nanotechnology carried out in contemporary physics, all integrated as a multidisciplinary knowledge applied to food. Acoustic waves have a spectrum called ultrasound, with an approximate frequency range between 20 kHz and 1 GHz, and this is divided into low-intensity ultrasound (LIU), whose objective is to characterize materials. On the contrary, high-intensity ultrasound (HIU) has the objective of carrying out destructive tests, modifying the study samples. This happens because the HIU generates a phenomenon called acoustic cavitation, which consists of the generation, growth, and implosion of microbubbles, causing alterations in the near and far acoustic field. The proposed review focuses on the application of high-intensity ultrasound to be used in the food industry. Subsequently, a brief approach is made to nanotechnology and nanomaterials and how they have been incorporated into the food industry.

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Section: Figure 13 Dimension Comparisonmentioning

confidence: 99%

High-Intensity Ultrasound and Its Interaction with Foodstuff and Nanomaterials

Rentería‐Monterrubio¹,

Chávez‐Martínez²,

Juárez-Moya³

et al. 2022

Trends and Innovations in Food Science

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“…The development of products containing nanoparticles (i.e., less than 100 nm in short diameter) has expanded significantly in various industries [1]. For example, amorphous silica nanoparticles are frequent components of cosmetics [2] and foods [3].…”

Section: Introductionmentioning

confidence: 99%

Amorphous silica nanoparticles (nSP50) exacerbate hepatic damage through the activation of acquired cell-mediated immunity

et al. 2022

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Due to their innovative functions, the use of nanoparticles in various industries has been expanding. However, a key concern is whether nanoparticles induce unexpected biological effects. Although many studies have focused on innate immunity, information on whether nanoparticles induce biological responses through effects on acquired immunity is sparse. Here, to assess the effects of amorphous silica nanoparticles on acquired immunity, we analyzed changes in acute toxicities after pretreatment with amorphous silica nanoparticles (50 nm in diameter; nSP50). Pretreatment with nSP50 biochemically and pathologically exacerbated nSP50-induced hepatic damage in immunocompetent mice. However, pretreatment with nSP50 did not exacerbate hepatic damage in immunodeficient mice. Consistent with this, the depletion of CD8+ cells with an anti-CD8 antibody in animals pretreated with nSP50 resulted in lower plasma levels of hepatic injury markers such as ALT and AST after an intravenous administration than treatment with an isotype-matched control antibody. Finally, stimulation of splenocytes promoted the release of IFN-γ in nSP50-pretreated mice regardless of the stimulator used. Moreover, the blockade of IFN-γ decreased plasma levels of ALT and AST levels in nSP50-pretreated mice. Collectively, these data show that nSP50-induced acquired immunity leads to exacerbation of hepatic damage through the activation of cytotoxic T lymphocytes.

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