Nanogels fabricated by lysozyme and sodium carboxymethyl cellulose for 5-fluorouracil controlled release

Preparation and evaluation of chitosan-based nanogels/gels for oral delivery of myricetin

“…4 may be caused by the addition of β-GP and the gelation process. Moreover, electrostatic attraction, hydrogen bonding, and hydrophobic interactions in CS/β-GP gels may also lead to the porous skeleton structure (Zhao et al, 2009;Zhu et al, 2013).…”

Curcumin encapsulated in the complex of lysozyme/carboxymethylcellulose and implications for the antioxidant activity of curcumin

“…The particle sizes and zeta potentials of Ly-CMC coacervates were not affected after Cur encapsulation (Table 1). The polydispersity indexes (PDI) of the coacervates were all larger than 0.5, indicating that nonuniform complex produced because of the unevenlengths of CMC chains (Zhu et al, 2013). The small particle size and strong negative charges of the coacervates indicated the stability of the solutions.…”

“…Carboxymethylcellulose (CMC), one of the cellulose derivatives, is a typical anionic polysaccharide, and has wide applications in the food industry (Geng et al, 2014;Song & Chen, 2015). Besides, CMC was often used as a potential carrier material due to its good biocompatibility, biodegradability and low immunogenicity (Cai et al, 2011;Song, Zhou & Chen, 2012;Zhu et al, 2013). The characteristics of CMC are closely related to the degree of substitution (DS), defined as the carboxymethyl groups per repeating glucoside unit.…”

Self-assembled lysozyme/carboxymethylcellulose nanogels for delivery of methotrexate

“…[7,8]. It is facile to create NGs using self-assembly of biopolymers [9]. The self-assembly of natural proteins and polysaccharides is widely used in biological and industrial fields, because the assembled coacervates can enhance emulsibility, solubility and stability of proteins at a broad range of pH [10,11].…”

“…Carboxymethylcellulose (CMC), which has a number of carboxymethyl groups and strong negative charges, can be easily dissolved in water [17]. Furthermore, CMC was reported as a potential material of carrier because of its good biocompatibility, biodegradability and low immunogenicity [9,18]. Therefore, it seems that Ly and CMC are ideal candidates for preparing NGs by self-assembly.…”