“…Its daily application as condiment and spice has chemopreventive and chemotherapeutic which candidate it for treatment of ailments such as lung cancer, skin and liver diseases [13][14][15]. Various role including antioxidant, anti-inflammatory, antibacterial, antiviral, anti-atherosclerotic, anti-arthriticagent and anticancer activities [16][17][18][19] are logical reasons for its extensive application and encourage researchers to design an accurate approach for preconcentration and quantification of curcumin in low level in complicated matrices. Several methods such as high-performance liquid chromatography [20][21][22], thin layer chromatography [23], UV-Vis spectrophotometry [24], HPTLC [25], 2-D flash liquid chromatography [26] and spectrofluorimetry [27,28] are applied for this regard.…”