Nanocrystalline silver dressing and subatmospheric pressure therapy following neoadjuvant radiation therapy and surgical excision of a feline injection site sarcoma

Woods, Samantha; Marques, Ana Isabel de Castro; Renwick, M. G.; Argyle, Sally A.; Yool, D. A.

doi:10.1177/1098612x12439269

Cited by 9 publications

(4 citation statements)

References 24 publications

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“…Numerous publications have reported the beneficial effect of NPWT on the healing of complicated wounds in humans and animals, 1-20 but information regarding cats was limited to a number of case reports and a case study. 17,19,[28][29][30] Here, we demonstrated faster wound closure in cats undergoing NPWT compared with foamtreated animals.…”

Section: Discussionmentioning

confidence: 93%

Retrospective comparison of negative pressure wound therapy and silver-coated foam dressings in open-wound treatment in cats

Nolff

Fehr

Reese

et al. 2016

Journal of Feline Medicine and Surgery

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Objectives The objective of this study was to evaluate negative pressure wound therapy (NPWT) for the treatment of complicated wounds in cats. Methods Twenty cats undergoing open-wound treatment in two clinics were classed according to treatment method: NPWT (group A, n = 10) and polyurethane foam dressing (group B, n = 10). Pairs of patients from each group were matched based on wound conformation, localisation and underlying cause. Cats from both groups were compared in terms of duration of previous treatment, time to closure and complications. Results Signalment, duration of previous treatment, antibiotic and antiseptic treatment, and bacterial status were comparable between groups. Total time to wound closure was significantly shorter ( P = 0.046, strong effect size; Cohen d = 0.8) in group A (25.8 days, range 11.0-57.0 days) compared with group B (39.5 days, range 28.0-75.0 days). NPWT-treated wounds suffered fewer complications and became septic less frequently during treatment compared with wounds treated with a foam dressing. The progression of fat tissue necrosis was particularly well controlled under NPWT, resulting in fewer deaths due to this condition in this group. However, although a strong effect of NPWT on the progression of infection, fever and sepsis was detected (Cramer-V 0.5), this difference was not significant. Conclusions and relevance This study demonstrated that time to healing was considerably shorter, and complication rate lower, in NPWT-treated animals compared with foam dressing-treated cats. In particular, the effective management of infection by NPWT emphasises the value of NPWT in the treatment of cats suffering from infected wounds.

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Section: Discussionmentioning

confidence: 93%

Retrospective comparison of negative pressure wound therapy and silver-coated foam dressings in open-wound treatment in cats

Nolff

Fehr

Reese

et al. 2016

Journal of Feline Medicine and Surgery

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“…Similarly, the same authors further demonstrated that nanosilver, as mycoad, can be useful in reducing the adverse effects of aflatoxin on blood parameters in chickens that are affected with aflatoxicosis [ 124 ]. The combination of nanocrystalline silver and subatmospheric pressure therapy shows significant effect in cat after following tumour removal and radiation therapy [ 125 ].…”

Section: Types Of Various Nanomaterials Used In Veterinary Medicinmentioning

confidence: 99%

Theranostics Aspects of Various Nanoparticles in Veterinary Medicine

Bai

Lin

Huang

et al. 2018

IJMS

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Nanoscience and nanotechnology shows immense interest in various areas of research and applications, including biotechnology, biomedical sciences, nanomedicine, and veterinary medicine. Studies and application of nanotechnology was explored very extensively in the human medical field and also studies undertaken in rodents extensively, still either studies or applications in veterinary medicine is not up to the level when compared to applications to human beings. The application in veterinary medicine and animal production is still relatively innovative. Recently, in the era of health care technologies, Veterinary Medicine also entered into a new phase and incredible transformations. Nanotechnology has tremendous and potential influence not only the way we live, but also on the way that we practice veterinary medicine and increase the safety of domestic animals, production, and income to the farmers through use of nanomaterials. The current status and advancements of nanotechnology is being used to enhance the animal growth promotion, and production. To achieve these, nanoparticles are used as alternative antimicrobial agents to overcome the usage alarming rate of antibiotics, detection of pathogenic bacteria, and also nanoparticles being used as drug delivery agents as new drug and vaccine candidates with improved characteristics and performance, diagnostic, therapeutic, feed additive, nutrient delivery, biocidal agents, reproductive aids, and finally to increase the quality of food using various kinds of functionalized nanoparticles, such as liposomes, polymeric nanoparticles, dendrimers, micellar nanoparticles, and metal nanoparticles. It seems that nanotechnology is ideal for veterinary applications in terms of cost and the availability of resources. The main focus of this review is describes some of the important current and future principal aspects of involvement of nanotechnology in Veterinary Medicine. However, we are not intended to cover the entire scenario of Veterinary Medicine, despite this review is to provide a glimpse at potential important targets of nanotechnology in the field of Veterinary Medicine. Considering the strong potential of the interaction between the nanotechnology and Veterinary Medicine, the aim of this review is to provide a concise description of the advances of nanotechnology in Veterinary Medicine, in terms of their potential application of various kinds of nanoparticles, secondly we discussed role of nanomaterials in animal health and production, and finally we discussed conclusion and future perspectives of nanotechnology in veterinary medicine.

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“…Advances in biotechnology have enabled incorporation of ionisable silver into fabrics for clinical use to reduce the risk of nosocomial infections and for personal hygiene. 54 Although veterinary use of silver has not yet taken off, in 2012, Woods et al 57 reported the use of a combination of nanocrystalline silver dressing and subatmospheric pressure therapy to treat a resistant wound infection, following tumour removal and radiation therapy, in a difficult-to-manage surgical site in a cat.…”

Section: Essential Oilsmentioning

confidence: 99%