Nanocrystalline hydroxyapatite ceramics

Фомин, А. С.; Баринов, С. М.; Иевлев, В. М.; Смірнов, В. В.; Михайлов, Б. П.; Kutsev, S. V.; Belonogov, E. K.; Дроздова, Н. А.

doi:10.1134/s0020168509100203

Cited by 8 publications

(4 citation statements)

References 3 publications

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“…Ca/P ratios of 1.89 and 2.38 were calculated for HA without and with collagen, respectively. The first value is near the theoretical value (1.67) considering the repeat unit of the HA chemical structure-Ca 10 (PO 4 ) 6 (OH) 2 [3]. The addition of collagen influenced the HA chain growth.…”

Section: Energy-dispersive X-ray Spectroscopy (Edx)mentioning

confidence: 63%

“…Calcium phosphate apatites make up an important class of biomaterial, with hydroxyapatite (HA), Ca 10 (PO 4 ) 6 (OH) 2 , being the most important due to its similarities with the mineral constituents of bone tissue and tooth enamel and dentin [1][2][3]. HA has excellent biocompatibility, displaying properties of osteoinduction, osteoconduction and osteointegration without cellular toxicity [4,5].…”

Section: Introductionmentioning

confidence: 99%

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<i>In Situ</i> Hydroxyapatite Synthesis: Influence of Collagen on Its Structural and Morphological Characteristic

Mendes¹,

Ribeiro²,

Marques³

2012

MSA

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Hydroxyapatite (HA) was synthesized in situ by the precipitation method, with and without the presence of collagen (COLL), to study its influence on HA’s structural and morphological characteristics. The material was characterized by energy dispersive X-ray spectroscopy (EDX), Fourier transform infrared spectroscopy (FT-IR), wide-angle X-ray diffraction (WAXD), thermogravimetric analysis (TG) and scanning electron microscopy (SEM). The Ca/P molar ratio was influenced by collagen addition—1.89 and 2.38 for samples without and with collagen, respectively. The WAXD pattern revealed better resolution and intensity besides higher crystallinity degree of the HA in the presence of collagen. The photomicrographs showed a strong influence of collagen on the HA morphology

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Section: Energy-dispersive X-ray Spectroscopy (Edx)mentioning

confidence: 63%

Section: Introductionmentioning

confidence: 99%

<i>In Situ</i> Hydroxyapatite Synthesis: Influence of Collagen on Its Structural and Morphological Characteristic

Mendes¹,

Ribeiro²,

Marques³

2012

MSA

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“…The ratio of calcium to phosphorus is higher than in hydroxyapatite of stoichiometric composition (1.67). It is typical for apatites derived from biogenic raw materials and is caused by anionic and cationic substitutions in the crystal lattice of hydroxyapatite [20].…”

Section: Resultsmentioning

confidence: 99%

“…The spectrum of the composite coating (figure 2) exhibits absorption bands corresponding to the VDF-TeFE co-polymer, which macromolecules are in conformations with ferroelectric properties, at 1328, 880, 840 (TTT conformation) and 822 cm −1 (T 3 GT 3 Gconformation) [30,31]. An intense band characteristic of polymer molecules with long trans sequences is observed at 840 cm −1 , indicating that the electrically active (TTT) conformation is predominant [26,27]. Absorption bands corresponding to the stretching and bending of the PO 4 3− moiety are observed at 1026, 1090, 963, 600, 563 and 520 cm −1 [28,29].…”

Section: Investigation Of Physicochemical Propertiesmentioning

confidence: 99%

Flexible intramedullary nails for limb lengthening: a comprehensive comparative study of three nails types

et al. 2019

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A comparative study of flexible intramedullary nails (FIN) used for lengthening of long tubular bones in children is presented. It has been found that the presence of calcium phosphate coating obtained by micro-arc oxidation or a composite coating based on a copolymer of vinylidene fluoride with tetrafluoroethylene and hydroxyapatite on the surface of FIN significantly enhances the formation of bone regenerate in the area of osteotomy during limb lengthening by combined osteosynthesis. The investigation of physico-chemical properties of FIN with calcium phosphate coating obtained by micro-arc oxidation demonstrated that improved bone tissue formation is due to favourable conditions for adhesion, proliferation, and differentiation of MMSCs into osteoblasts on the coating surface. Composite coatings stimulated the formation of bone tissue only in vivo, mainly due to the piezoelectric properties of the copolymer of vinylidene fluoride with tetrafluoroethylene. Keywords: flexible intramedullary nails, calcium phosphate coating, vinylidene fluoride -tetrafluoroethylene, piezoelectric, combined limb lengthening 1. Introduction Deterioration of the environmental situation, primarily in industrialized countries, and rising frequency of genetic diseases provoke an increase in the number of patients and the severity of orthopaedic pathologies associated with congenital shortening and deformities of the limbs. The limb shortening, progressing as a person develops, leads to pathological changes in the entire biomechanical system. For example, overloading a healthy limb and skewing of the pelvis cause the development of pathologies associated with deformations and dislocation of the healthy hip, leading to a decrease in the quality of life. Thus, the restoration of the limb length allows solving not only the problems of orthopaedic and biomechanical recovery, but also the problem of social rehabilitation and patient's integration into society. For congenital limb length discrepancy the correction of pathology in the affected segment and functionally related elements of the biomechanical system could be done only through surgical interventions. A major contribution for solving this problem was made by outstanding orthopaedic surgeon G.A. Ilizarov, who developed the methods of surgical treatment based on distraction osteogenesis [1,2]. The recent development of G.A Ilizarov method resulted in development of combined osteosynthesis. In this approach, the external fixation devices and thin (up to 2.5 mm) flexible intramedullary nails (FIN) implanted into medullary canal of the tubular bone are used [3,4]. The circular external fixator allows to achieve the high stability of the bone fragments positioning. FIN located in the anatomical zone with multipotent cells depot and a good blood supply, allows to control the histogenesis aimed at bone tissue production. The unique anatomical location of FIN makes it one of the key elements of the combined osteosynthesis. FIN properties largely determine the clinical success of the limb leng...

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Virgin and Recycled Polymers Applied to Advanced Nanocomposites

Mendes

Cestari

2017

Handbook of Composites From Renewable Materials

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Nanocrystalline hydroxyapatite ceramics

Cited by 8 publications

References 3 publications

<i>In Situ</i> Hydroxyapatite Synthesis: Influence of Collagen on Its Structural and Morphological Characteristic

<i>In Situ</i> Hydroxyapatite Synthesis: Influence of Collagen on Its Structural and Morphological Characteristic

Flexible intramedullary nails for limb lengthening: a comprehensive comparative study of three nails types

Virgin and Recycled Polymers Applied to Advanced Nanocomposites

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Nanocrystalline hydroxyapatite ceramics

Cited by 8 publications

References 3 publications

&lt;i&gt;In Situ&lt;/i&gt; Hydroxyapatite Synthesis: Influence of Collagen on Its Structural and Morphological Characteristic

&lt;i&gt;In Situ&lt;/i&gt; Hydroxyapatite Synthesis: Influence of Collagen on Its Structural and Morphological Characteristic

Flexible intramedullary nails for limb lengthening: a comprehensive comparative study of three nails types

Virgin and Recycled Polymers Applied to Advanced Nanocomposites

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Product

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<i>In Situ</i> Hydroxyapatite Synthesis: Influence of Collagen on Its Structural and Morphological Characteristic

<i>In Situ</i> Hydroxyapatite Synthesis: Influence of Collagen on Its Structural and Morphological Characteristic