Nanocomposite of functional silver metal containing curcumin biomolecule model systems: Protein BSA bioavailability

Shedge, Amol A.; Pansare, Shubham V.; Khairkar, Shyam R.; Chhatre, Shraddha Y.; Chakrabarti, Subhananda; Nagarkar, Amit A.; Pansare, Amol V.; Patil, Vishwanath R.

doi:10.1016/j.jinorgbio.2020.111210

Cited by 17 publications

(12 citation statements)

References 34 publications

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“…† The positive values of Δ S 0 (0.533 kJ mol −1 K −1 ) and Δ H 0 (130.48 kJ mol −1 ) indicate that binding occurs via hydrophobic interactions. 46 Negative values of Δ G 0 suggest that the binding between α-AA and hs-DNA occurs spontaneously.…”

Section: Methodsmentioning

confidence: 99%

Deciphering the sensing of α-amyrin acetate with hs-DNA: a multipronged biological probe

et al. 2022

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Section: Methodsmentioning

confidence: 99%

Deciphering the sensing of α-amyrin acetate with hs-DNA: a multipronged biological probe

et al. 2022

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“…A spontaneous process will show a decrease in ∆G° and ∆H° values with increasing Fig. 7 Adsorption mechanisms of MG and MB dye on surface of composites temperatures [30][31][32][33]. The temperatures used in the thermodynamic study were 300 and 310 K. The thermodynamic parameters were calculated based on the following equations: Table 1 lists down the values for the thermodynamic parameters.…”

Section: Thermodynamic Parametersmentioning

confidence: 99%

Biological macromolecule chitosan grafted co-polymeric composite: bio-adsorption probe on cationic dyes

et al. 2021

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Chitosan biological macromolecule is a versatile polymer; chemical modification has been carried out that lead to the formation of chitosan grafted polymers composites (Chito-g-PC). We proposed synthesis of six various Chito-g-PC as sorbents for toxic dyes. A novel graft copolymerization method based on radical polymerization with vinyl monomer like acrylic acid, acrylamide, N-isopropylacrylamide, methacrylic acid and polyacrylonitrile were utilized in order to address the large amount of swelling at four different pH buffers solution. The effect of initiator and monomer concentration, time and temperature on % grafting and % grafting efficiency were performed. Comparative characterization of Chito and Chito-g-PC were evaluated by SEM, XRD and FTIR, as well as solubility characteristics of the composites were determined by various pH buffer solution. Cationic toxic dyes Malachite green (MG) and Methylene blue (MB) were selected as the sorbet, and Chito-g-PC were used as biosorbents. Thermodynamic analysis showed that the sorption process was spontaneous and endothermic with an increased randomness. The sorption experiments were realized with six different Chito-g-PC for MG and MB at various pH.

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“…However, due to its hydrophobicity, it is barely soluble in water. Poor solubility, together with rapid metabolism and systemic elimination, results in poor bioavailability in physiologic conditions [ 4 , 5 ]. On the other hand, curcumin is utilized not only as a spice and coloring agent in food [ 6 ], but also in a number of pharmaceutic applications due to its numerous biological activities, including antioxidant, anticancer, anti-inflammatory and antimicrobial properties [ 4 , 5 , 6 , 7 , 8 ].…”

Section: Introductionmentioning

confidence: 99%

“…Poor solubility, together with rapid metabolism and systemic elimination, results in poor bioavailability in physiologic conditions [ 4 , 5 ]. On the other hand, curcumin is utilized not only as a spice and coloring agent in food [ 6 ], but also in a number of pharmaceutic applications due to its numerous biological activities, including antioxidant, anticancer, anti-inflammatory and antimicrobial properties [ 4 , 5 , 6 , 7 , 8 ]. These desirable characteristics stimulated research aimed to develop polymeric films added with curcumin with the purpose of getting materials with antioxidant and antimicrobial properties [ 3 , 9 , 10 , 11 ].…”

Section: Introductionmentioning

confidence: 99%

Curcumin-Functionalized Gelatin Films: Antioxidant Materials with Modulated Physico-Chemical Properties

et al. 2021

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In this paper we used curcumin as a functionalizing agent of gelatin films with the aim to get antioxidant materials with modulated physico-chemical properties. To this aim, we prepared gelatin films at different contents of curcumin up to about 1.2 wt%. The as-prepared films, as well as glutaraldehyde crosslinked films, were submitted to several tests: swelling, water solubility, differential scanning calorimetry, X-ray diffraction, mechanical tests and curcumin release. The radical scavenging activity of the as-prepared films is similar to that of free curcumin, indicating remarkable antioxidant properties. All the other tested properties vary as a function of curcumin content and/or the presence of the crosslinking agent. In particular, the films exhibit sustained curcumin release in different solvents. Thanks to its biocompatibility, biodegradability and lack of antigenicity, gelatin uses span from food processing to packaging and biomaterials. It follows that the modulated properties exhibited by the functionalized materials developed in this work can be usefully employed in different application fields.

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Nanocomposite of functional silver metal containing curcumin biomolecule model systems: Protein BSA bioavailability

Cited by 17 publications

References 34 publications

Deciphering the sensing of α-amyrin acetate with hs-DNA: a multipronged biological probe

Deciphering the sensing of α-amyrin acetate with hs-DNA: a multipronged biological probe

Biological macromolecule chitosan grafted co-polymeric composite: bio-adsorption probe on cationic dyes

Curcumin-Functionalized Gelatin Films: Antioxidant Materials with Modulated Physico-Chemical Properties

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