Nanocolloids in Natural Water: Isolation, Characterization, and Toxicity

Ouyang, Shaohu; Hu, Xiangang; Zhou, Qixing; Li, Xiaokang; Miao, Xinyu; Zhou, Ruiren

doi:10.1021/acs.est.7b05364

Cited by 50 publications

(50 citation statements)

References 83 publications

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“…DEGs were analyzed using GO functional category enrichment (Figure ). Cell wall structure and membrane would be changed in response to the invasion of AgNPs, , consistent with the consequence that DEGs were enriched to “cell wall organization or biogenesis”, “extrinsic component of membrane”, and “plasma membrane bounded cell projection” functional category (Figure ). More differential genes are enriched into the related functions of the cell wall and plasma membrane in single exposure.…”

Section: Resultssupporting

confidence: 71%

Transcriptomics and Metabolomics Revealed the Biological Response of Chlorella pyrenoidesa to Single and Repeated Exposures of AgNPs at Different Concentrations

Cao

Huang

Wang

et al. 2021

Environ. Sci. Technol.

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Increased release of engineered nanoparticles (ENPs) from widely used commercial products has threatened environmental health and safety, particularly the repeated exposures to ENPs with relatively low concentration. Herein, we studied the response of Chlorella pyrenoidesa (C. pyrenoidesa) to single and repeated exposures to silver nanoparticles (AgNPs). Repeated exposures to AgNPs promoted chlorophyll a and carotenoid production, and increased silver accumulation, thus enhancing the risk of AgNPs entering the food chain. Notably, the extracellular polymeric substances (EPS) content of the 1-AgNPs and 3-AgNPs groups were dramatically increased by 119.1% and 151.5%, respectively. We found that C. pyrenoidesa cells exposed to AgNPs had several significant alterations in metabolic process and cellular transcription. Most of the genes and metabolites are altered in a dose-dependent manner. Compared with the control group, single exposure had more differential genes and metabolites than repeated exposures. 562, 1341, 4014, 227, 483, and 2409 unigenes were differentially expressed by 1–0.5-AgNPs, 1–5-AgNPs, 1–10-AgNPs, 3–0.5-AgNPs, 3–5-AgNPs, and 3–10-AgNPs treatment groups compared with the control. Metabolomic analyses revealed that AgNPs altered the levels of sugars and amino acids, suggesting that AgNPs reprogrammed carbon/nitrogen metabolism. The changes of genes related to carbohydrate and amino acid metabolism, such as citrate synthase (CS), isocitrate dehydrogenase (IDH1), and malate dehydrogenase (MDH), further supported these results. These findings elucidated the mechanism of biological responses to repeated exposures to AgNPs, providing a new perspective on the risk assessment of nanomaterials.

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Section: Resultssupporting

confidence: 71%

Transcriptomics and Metabolomics Revealed the Biological Response of Chlorella pyrenoidesa to Single and Repeated Exposures of AgNPs at Different Concentrations

Cao

Huang

Wang

et al. 2021

Environ. Sci. Technol.

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“…0.25)). The detection limit was comparable to the predicted concentration of artificial SiO 2 nanoparticles and natural Si-containing nanocolloids, , implying the potential application of the CSNERS method toward practical detection. Moreover, Si usually exists in plants with a high background concentration (100–600 mg/kg dry weight) .…”

Section: Resultsmentioning

confidence: 99%

Selectively Tracking Nanoparticles in Aquatic Plant Using Core–Shell Nanoparticle-Enhanced Raman Spectroscopy Imaging

Yang

et al. 2021

ACS Nano

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Nanoparticles contribute to enormous environmental processes, but, due to analytical challenges, the understanding of nanoparticle fate remains elusive in complex environmental matrices. To address the challenge, a core–shell nanoparticle-enhanced Raman spectroscopy (CSNERS) imaging method was developed to selectively track prevalent SiO2 nanoparticles in an aquatic plant, Lemna minor. By encapsulating gold nanoparticles and Raman reporters inside, the resonance Raman signature was enhanced, thus enabling the sensitive and selective detection of SiO2 nanoparticles at an environmentally relevant concentration. The panoramic visualization of the translocation pathway of nanoparticles shows an unexpected, fast (in hours) and a preferential accumulation of nanoparticles on the node, leaf edge, root cap, etc., implying the ability of CSNERS to spectroscopically determine nanotoxicity. The core–shell design in CSNERS was capable of multiplex labeling two differently charged nanoparticles and distinguishing their biobehavior simultaneously. Meanwhile, the CSNERS method can be further applied for a variety of nanoparticles, implying its promising applications for nanotoxicity research and biogeochemical study.

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“…In wound dressings, nanocolloids are used as antimicrobial agents, as they can penetrate eukaryotic and prokaryotic cells due to the perpetual Brownian motion [11]. However, some authors point to their potential cytotoxicity, limiting their usage on a mass scale [157].…”

Section: Modern Wound Dressing Materials and Nanomaterialsmentioning

confidence: 99%

Composite Membrane Dressings System with Metallic Nanoparticles as an Antibacterial Factor in Wound Healing

et al. 2022

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Wound management is the burning problem of modern medicine, significantly burdening developed countries’ healthcare systems. In recent years, it has become clear that the achievements of nanotechnology have introduced a new quality in wound healing. The application of nanomaterials in wound dressing significantly improves their properties and promotes the healing of injuries. Therefore, this review paper presents the subjectively selected nanomaterials used in wound dressings, including the metallic nanoparticles (NPs), and refers to the aspects of their application as antimicrobial factors. The literature review was supplemented with the results of our team’s research on the elements of multifunctional new-generation dressings containing nanoparticles. The wound healing multiple molecular pathways, mediating cell types, and affecting agents are discussed herein. Moreover, the categorization of wound dressings is presented. Additionally, some materials and membrane constructs applied in wound dressings are described. Finally, bacterial participation in wound healing and the mechanism of the antibacterial function of nanoparticles are considered. Membranes involving NPs as the bacteriostatic factors for improving wound healing of skin and bones, including our experimental findings, are discussed in the paper. In addition, some studies of our team concerning the selected bacterial strains’ interaction with material involving different metallic NPs, such as AuNPs, AgNPs, Fe3O4NPs, and CuNPs, are presented. Furthermore, nanoparticles’ influence on selected eukaryotic cells is mentioned. The ideal, universal wound dressing still has not been obtained; thus, a new generation of products have been developed, represented by the nanocomposite materials with antibacterial, anti-inflammatory properties that can influence the wound-healing process.

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Nanocolloids in Natural Water: Isolation, Characterization, and Toxicity

Cited by 50 publications

References 83 publications

Transcriptomics and Metabolomics Revealed the Biological Response of Chlorella pyrenoidesa to Single and Repeated Exposures of AgNPs at Different Concentrations

Transcriptomics and Metabolomics Revealed the Biological Response of Chlorella pyrenoidesa to Single and Repeated Exposures of AgNPs at Different Concentrations

Selectively Tracking Nanoparticles in Aquatic Plant Using Core–Shell Nanoparticle-Enhanced Raman Spectroscopy Imaging

Composite Membrane Dressings System with Metallic Nanoparticles as an Antibacterial Factor in Wound Healing

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