Nanocapsule formation by electrospraying

Tapia-Hernández, José Agustín; Rodríguez-Félix, Francisco; Katouzian, Iman

doi:10.1016/b978-0-12-809436-5.00009-4

Cited by 25 publications

(17 citation statements)

References 130 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…At a distance of 10 cm, average diameters were 150 ± 31.5, 188.3 ± 30.8, 244.2 ± 26.2, 295.5 ± 32.3, and 306.3 ± 35.8 nm, and at a distance of 15 cm, these were 174.2 ± 23.5, 203.8 ± 18.2, 265.1 ± 27.3, 312.7 ± 33.2, and 332.9 ± 30.1 nm for concentrations of 1, 2, 3, 4, and 5% w/v, respectively. Studies report that needle distance of the collector and solvent evaporation exert a significant impact on particle size and distribution with three behaviors as follows: the first behavior, were at short distance (<10 cm) and high solvent evaporation, a smaller diameter is obtained; the second, if the collector distance is very short (5 cm), it will not be possible to evaporate all of the solvent; thus, the particle will be unstable and the size will be larger (Costamagna et al., ; Ghayempour, & Mortazavi, ), and, in the third behavior, if the collector distance is long (>10 cm) with low solvent evaporation, it can volatilize the solvent and the polymer particle encourages fission (Chen et al., ; Tapia‐Hernández et al., ). Similar studies that have reported distances of 10 cm for zein nanoparticles were those of do Evangelho et al.…”

Section: Resultsmentioning

confidence: 99%

“…In the electrospraying process, if it increases the concentration of the components, larger particles are obtained, while on increasing the voltage, the viscosity decreases and smaller particles are obtained (Ghayempour & Mortazavi, 2013;Tapia-Hernández, Rodríguez-Félix, & Katouzian, 2017). Figure 4 depicts the impact of particle size due to the increase in viscosity by the increase in the concentration of GA where, at a lower concentration (1% w/v) of GA, there was lower viscosity with stable cone-jet mode and smaller particle diameter.…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Gallic Acid‐Loaded Zein Nanoparticles by Electrospraying Process

Tapia-Hernández

Del‐Toro‐Sánchez

Cinco-Moroyoqui

et al. 2019

Journal of Food Science

View full text Add to dashboard Cite

Currently, electrospraying is a novel process for obtaining the nanoparticles from biopolymers. Zein nanoparticles have been obtained by this method and used to protect both hydrophilic and hydrophobic antioxidant molecules from environmental factors. The objective of this work was to prepare and characterize gallic acid‐loaded zein nanoparticles obtained by the electrospraying process to provide protection to gallic acid from environmental factors. Thus, it was related to the concentration of gallic acid in physicochemical and rheological properties of the electrosprayed solution, and also to equipment parameters, such as voltage, flow rate, and distance of the collector in morphology, and particle size. The physicochemical properties showed a relationship in the formation of a Taylor cone, in which at a low concentration of gallic acid (1% w/v), low viscosity (0.00464 ± 0.00001 Pa·s), and density (0.886 ± 0.00002 g/cm3), as well as high electrical conductivity (369 ± 4.3 µs/cm), forms a stable cone‐jet mode. The rheological properties and the Power Law model of the gallic acid‐zein electrosprayed solution demonstrated Newtonian behavior (n = 1). The morphology and size of the particle were dependent on the concentration of gallic acid. Electrosprayed parameters with high voltage (15 kV), low flow rate (0.1 mL/hr), and short distance (10 cm) exhibited a smaller diameter and spherical morphology. FT–IR showed interaction in the gallic acid‐loaded zein nanoparticle by hydrogen bonds. Therefore, the electrospraying process is a feasible technique for obtaining gallic acid‐loaded zein nanoparticles and providing potential protection to gallic acid from environmental factors.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Gallic Acid‐Loaded Zein Nanoparticles by Electrospraying Process

Tapia-Hernández

Del‐Toro‐Sánchez

Cinco-Moroyoqui

et al. 2019

Journal of Food Science

View full text Add to dashboard Cite

show abstract

“…Finally, the highly charged liquid droplets disperse radially on the collector plate, due to Coulomb's repulsion of charges (Alehosseini, Ghorani, Sarabi-Jamab, & Tucker, 2017;Jayaraman et al, 2015). The parameters that exert an influence on the control of particle size are equipment parameters (applied voltage, flow rate, and distance of the collector), parameters of the polymer solution (concentration, viscosity, density, conductivity, and surface tension), and environmental parameters (humidity and temperature; Jaworek, Sobczyk, & Krupa, 2018;Tapia-Hernández, Rodríguez-Félix, & Katouzian, 2017). For instance, Liu et al (2018) elaborated nanoparticles by coaxial electrospray using 12% zein and 3% (w/v) tamoxifen citrate and concluded that this technique produces particles with better quality in terms of particle size, distribution of size, and morphology.…”

Section: Introductionmentioning

confidence: 99%

Preparation and Characterization of Quercetin‐Loaded Zein Nanoparticles by Electrospraying and Study of In Vitro Bioavailability

Rodríguez-Félix

Del‐Toro‐Sánchez

Cinco-Moroyoqui

et al. 2019

Journal of Food Science

View full text Add to dashboard Cite

Quercetin is a hydrophobic flavonoid with high antioxidant activity. However, for biological applications, the bioavailability of quercetin is low due to physiological barriers. For this reason, an alternative is the protection of quercetin in matrices of biopolymers as zein. The objective of this work was to prepare and characterize quercetin‐loaded zein nanoparticles by electrospraying and its study of in vitro bioavailability. The physicochemical parameters such as viscosity, density, and electrical conductivity of zein solutions showed a dependence of the ethanol concentration. In addition, rheological parameters demonstrated that solutions of zein in aqueous ethanol present Newtonian behavior, rebounding in the formation of nanoparticles by electrospraying, providing spherical, homogeneous, and compact morphologies, mainly at a concentration of 80% (v/v) of ethanol and of 5% (w/v) of zein. The size and shape of quercetin‐loaded zein nanoparticles were studied by transmission electron microscopy (TEM), observing that it was entrapped, distributed throughout the nanoparticle of zein. Analysis by Fourier transform‐infrared (FT‐IR) of zein nanoparticles loaded with quercetin revealed interactions via hydrogen bonds. The efficacy of zein nanoparticles to entrap quercetin was particularly high for all quercetin concentration evaluated in this work (87.9 ± 1.5% to 93.0 ± 2.6%). The in vitro gastrointestinal release of trapped quercetin after 240 min was 79.1%, while that for free quercetin was 99.2%. The in vitro bioavailability was higher for trapped quercetin (5.9%) compared to free quercetin (1.9%), than of gastrointestinal digestion. It is concluded, that the electrospraying technique made possible the obtention of quercitin‐loaded zein nanoparticles increasing their bioavailability. Practical Application This type of nanosystems can be used in the food and pharmaceutical industry. Quercetin‐loaded zein nanoparticles for its improvement compared to free quercetin can be used to decrease the prevalence of chronic degenerative diseases by increasing of the bioavailability of quercetin in the bloodstream. Other application can be as an antioxidant system in functional foods or oils to increase shelf life.

show abstract

“…The interested reader may consult some of the accounts of the effect of processing parameters on the properties of electro-spun or electro-sprayed materials; for a more detailed description, see the references [122,123,148].…”

Section: Fundamental Of Electro-hydrodynamic Process Encapsulationmentioning

confidence: 99%

Electro-Spinning and Electro-Spraying as Innovative Approaches in Developing of a Suitable Food Vehicle for Polyphenols-Based Functional Ingredients

Ghorbani¹,

Aleman²

2021

Bioactive Compounds - Biosynthesis, Characterization and Applications [Working Title]

View full text Add to dashboard Cite

With recent advances in medical and nutrition sciences, functional foods and nutraceuticals fortified with natural polyphenols have received a lot of attention from both health professionals and the common population in the last few years since their chemical structure allows them to exert various health effects (e.g., antioxidant, anti-inflammatory, immune, antitumor and prebiotic properties). Nonetheless, there are several hurdles to applications of polyphenols in the food system. The most critical hurdle includes polyphenols’ tendency to lose their anti-oxidative properties or bioactive functionalities during food processing, as well as inclusion of poly-phenol compounds may impart an astringent or bitter taste, or introduce a degree of brown coloring causing serious sensorial impacts on food products. On this basis, interest has increased in understanding the development of new and efficient food vehicles as delivery systems for polyphenols-based functional ingredients. In this context, one approach that could augment the growth of polyphenols-based functional foods is electro-hydrodynamic processing, as the most versatile method to produce nanoscale fibers or particulates suitable for application in food technology by encapsulation to form nanoscale delivery systems.

show abstract

Nanocapsule formation by electrospraying

Cited by 25 publications

References 130 publications

Gallic Acid‐Loaded Zein Nanoparticles by Electrospraying Process

Gallic Acid‐Loaded Zein Nanoparticles by Electrospraying Process

Preparation and Characterization of Quercetin‐Loaded Zein Nanoparticles by Electrospraying and Study of In Vitro Bioavailability

Electro-Spinning and Electro-Spraying as Innovative Approaches in Developing of a Suitable Food Vehicle for Polyphenols-Based Functional Ingredients

Contact Info

Product

Resources

About