Nano thick poly(ε-caprolactone)-poly(ethylene glycol) coatings developed by catalyst-free plasma assisted copolymerization process for biomedical applications

Cell Repellent Coatings Developed by an Open Air Atmospheric Pressure Non-Equilibrium Argon Plasma Jet for Biomedical Applications

“…A new peak was observed at 1 730 cm −1 , which corresponds to the stretching vibrations of carbonyl‐based species that was not present in DEGME monomer. The FTIR spectra of a typical AP argon plasma deposited PEG (ap‐DEG) was plotted as well as the spectra of typical low pressure inductively excited RF plasma deposited PEG (pDEGME) coatings in order to compare the retention of the chemical functionalities prepared under two different operating pressures (1 atm for APAPJ and 0.5 mbar for LP) and applied frequencies (18 kHz for APAPJ and 13.56 MHz for LP) while the plasma power was kept constant around ∼1 W (Figure ). In Figure , the reference spectra of DEGME monomer (measurement volume = 40 µL) was also reported for comparison purposes.…”

“…The cellular response of APAPJ deposited PEG (ap‐DEG) coatings was investigated in vitro using human ovarian carcinoma cell lines (NIH:OVCAR‐3). The ap‐DEG coatings were compared to the ones obtained at low pressure (pDEGME) in terms of surface chemical composition and their resulting cell repellent properties.…”

Cell Resistant Peptidomimetic Poly (2‐ethyl‐2‐oxazoline) Coatings Developed by Low Pressure Inductively Excited Pulsed Plasma Polymerization for Biomedical Purpose

“…The cell-surface interaction is a complicated phenomenon, which mostly depends on the surface chemistry, surface charge, wetability and roughness. [30,37,38] From surface wettability measurements, the hydrophilicity of 0.25, 1 and 2.5 W deposited ppEtOz coatings was relatively higher than the coatings deposited at higher powers (P eff > 2.5 W). For the coatings deposited at 0.25 W, we did not observe any C5 5O stretching corresponding to carbonyl groups which might be due to the fact as mentioned before that the energy per unit mass of the monomer being very low, the energy is not sufficient to open up the rings (ROP) and to obtain a polymer.…”

“…The schematics of plasma polymerization set up and technical details of the process have been provided in our earlier work. [29,30] Briefly, prior to each experimental run, the plasma reactor was scrubbed and cleaned with detergent and organic solvents and dried using compressed air. The plasma reactor was reassembled and cleaned further with 30 W Ar plasma discharge at 0.5 mbar pressure for 20 min.…”

Properties of a-C:H:O plasma polymer films deposited from acetone vapors

“…Recently, it was demonstrated that by using ester-containing monomers, amorphous oxygenated hydrocarbon plasma polymers (a-C:H:O) can be deposited that are rich in ester groups [4,5]. Such coatings are interesting as (bio-)degradable plasma polymers that can be used in applications such as drug delivery, tissue engineering or as temporary barriers.…”