Nano selenium improves humoral immunity, growth performance and breast-muscle selenium concentration of broiler chickens

Abstract

Context Selenium (Se) is an essential trace element and plays pivotal roles in poultry nutrition. Aims The present study was designed to compare the impact of dietary supplementation of different sources of Se on growth performance, Se concentration of breast meat, and immune response of broiler chickens. Methods In total, 300 1-day-old as hatched broilers were randomly allocated to six dietary treatments, with five replicates of 10 birds per each. The experimental diets were as follows: (1) corn–soybean meal-based diet supplemented with 0.30 mg/kg of sodium selenite, (2) basal diet supplemented with 0.30 mg/kg of Se-enriched yeast, and (3–6) basal diet supplemented with 0.15, 0.30, 0.90 and 1.50 mg/kg of nano-Se respectively. Humoral immunity was assessed by antibody titer against a 5% sheep red blood-cell suspension and cellular immunity was measured by administration of phytohaemagglutinin-p at 38 days. Key results Results indicated that during the periods from 1 to 10 days, from 11 to 24 days, from 25 to 42 days and from 1 to 42 days, average daily gain, average daily feed intake, and feed conversion ratio did not differ among the treatments (P > 0.05). Assessment of orthogonal contrasts at the whole phase of feeding showed that the average daily gain in the broilers fed organic Se was significantly (P < 0.05) higher than that in those fed inorganic Se, as well as nano-Se in comparison to organic Se; such effects were not observed in earlier feeding stages. Se supplementation significantly increased the Se concentration of breast muscle (P < 0.0001). The birds that received 1.50 mg/kg of diet nano-Se showed higher (P < 0.05) total immunoglobulin and IgG titers in primary and secondary immune responses against sheep erythrocytes respectively. Toe web swelling after 24 h and 48 h of receiving phytohaemagglutinin-p was not affected by Se supplementation (P > 0.05). Conclusions In conclusion, the addition of nano-Se gave better results than did inorganic (sodium selenite) and organic (yeast selenium) forms of Se in performance traits, breast meat Se concentration and antibody response of broilers. Implications Novel elemental nanometer particulates, including nano-Se, exhibit new characteristics and a different mode of actions in comparison with organic and inorganic forms of Se sources in poultry diets. Inclusion of the nano form of Se in broiler diets and study of productive performance, immunity responses and meat quality leads to improve balanced broiler diets formulation in view of Se.

Effects of different levels of nano-selenium on growth performance, antioxidant capacity, biochemical parameters, and selenium content in Landes geese

“…Not much is known about the NS influence on geese. Consistent with our findings, previous work has found no differences in growth parameters between broilers fed diets supplemented with varying levels of NS (Mohammadi et al, 2020;Bami et al, 2022). However, other studies have shown that dietary supplementation of NS had a significant effect on FBW, daily body weight gain, and feed conversion ratio (FCR).…”

Effects of selenoprotein extracts from Cardamine hupingshanensis on growth, selenium metabolism, antioxidant capacity, immunity and intestinal health in largemouth bass Micropterus salmoides

“…As an essential micronutrient, dietary Se plays crucial roles in promoting growth and maintaining normal physiological functions in different organisms ( 2 , 34 ). Numerous studies have demonstrated that dietary selenium can influence the growth and development of various aquatic and terrestrial animal species, including largemouth bass ( 1 ), European seabass ( Dicentrarchus labrax ) ( 3 ), rainbow trout ( Oncorhynchus mykiss ) ( 7 ), common carp ( Cyprinus carpio ) ( 35 ), grass carp ( Ctenopharyngodon idellus ) ( 36 ) and chicken ( 37 ). In line with these findings, our results also presented that 0.60 and 1.20 g/Kg SePCH (equivalent to 0.84-1.30 mg/kg) notably heightened WG and DGR, highlighting the role of adequate SePCH (0.60 and 1.20 g/Kg) could enhance the growth performance of largemouth bass ( 1 , 3 ).…”

Immunomodulatory effects of selenium‐enriched peptides from soybean in cyclophosphamide‐induced immunosuppressed mice

“…Since 1957, Se has been considered an essential trace element for many life forms and is crucial for human health. It has been proven that Se, as an essential micronutrient with antioxidant properties, can improve immune functions in the body by regulating humoral immunity, cellular immunity, and nonspecific immunity (Carlson et al., 2010 ; Esmail et al., 2020 ). Se plays an essential physiological role in the body in the form of selenoprotein (Zhang et al., 2021 ).…”