Nano/micro fluorhydroxyapatite crystal pastes in the treatment of dentin hypersensitivity: an in vitro study

Taha, Sahar; Han, Hua; Chang, Soo-Eun; Sovadinová, Iva; Kuroda, Kenichi; Langford, R. M.; Clarkson, Brian H.

doi:10.1007/s00784-015-1427-2

Cited by 17 publications

(13 citation statements)

References 38 publications

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“…In reviewing literature related to the present study, the occlusion abilities and acid resistant characteristics of Nano/micro fluorhyhydroxyapatite crystals, 26 nanohydroxyapatite/mesoporous 11 silica composite and zinc oxide hydroxyapatite paste 27 have shown promising results in the treatment of DH. Unlike the aforementioned materials, EB@TiO 2 bio composite had the advantage of being readily available since the bulk of the material is made from waste eggshell.…”

Section: Discussionmentioning

confidence: 90%

A novel application of nano eggshell/titanium dioxide composite on occluding dentine tubules: an in vitro study

et al. 2019

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To synthesize Nano eggshell-titanium-dioxide (EB@TiO2) biocomposite and to evaluate its effectiveness in occluding opened dentine tubules. EB@TiO2 was synthesized and characterized using X-ray diffraction (XRD), and Transmission Electron Microscope (TEM). Sixteen simulated bovine dentine discs were prepared and randomly assigned into four groups according to the following treatment (n = 4): Group 1: No treatment; Group 2: eggshell powder; Group 3: EB@TiO2; Group 4: Sensodyne. These were then agitated in a solution of 1g powder and 40mL water for 3hours. Thereafter, each dentine discs from the respective groups were post-treated for 5 min with 2wt% citric acid to test their acid resistant characteristics. Scanning Electron Microscope (SEM) was used to observe the effectiveness of occluded dentine preand post-treatment. The cytotoxicity of the synthesized EB@TiO2 was tested using NIH 3T3 assay. ANOVA was used to evaluate the mean values of the occluded area ratio and the data of MTS assay. This was followed by a multi-comparison test with Bonferroni correction (α = .05). The XRD confirmed that EB@TiO2 was successfully modified through ball-milling. The TEM revealed the presence of both spherical and irregular particle shape powders. The SEM result showed that EB@TiO2 could effectively occlude open dentine tubules. Equally, the result demonstrated that EB@TiO2 exhibited the highest acid resistant stability post-treatment. NIH 3T3 assay identified that EB@TiO2 had little effect on the NIH 3T3 cell line even at the highest concentration of 100µg/ml. This study suggests that the application of EB@TiO2 effectively occluded dentine tubules and the occlusion showed a high acid resistant stability.

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Section: Discussionmentioning

confidence: 90%

A novel application of nano eggshell/titanium dioxide composite on occluding dentine tubules: an in vitro study

et al. 2019

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“…In the available literature there are few papers on the potential use of FA or FHA in the treatment of hypersensitivity. Noteworthy is the study of Taha et al [49] in which the toothpastes containing nano- and microcrystalline FHA were investigated. It turned out that the obtained pastes did not show cytotoxicity.…”

Section: The Role Of Ha and Fa In Conservative Dentistrymentioning

confidence: 99%

Hydroxyapatite and Fluorapatite in Conservative Dentistry and Oral Implantology—A Review

2019

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Calcium phosphate, due to its similarity to the inorganic fraction of mineralized tissues, has played a key role in many areas of medicine, in particular, regenerative medicine and orthopedics. It has also found application in conservative dentistry and dental surgery, in particular, as components of toothpaste and mouth rinse, coatings of dental implants, cements, and bone substitute materials for the restoration of cavities in maxillofacial surgery. In dental applications, the most important role is played by hydroxyapatite and fluorapatite, i.e., calcium phosphates characterized by the highest chemical stability and very low solubility. This paper presents the role of both apatites in dentistry and a review of recent achievements in the field of the application of these materials.

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“…7,8 Based on this theory, the main strategy to treat DH is to reduce dentin permeability by blocking/occluding dentinal tubules. [9][10][11] Current materials for dentinal tubule occlusion include sodium fluoride/stannous fluoride, [12][13][14] strontium chloride/acetate, 15,16 potassium oxalate, [17][18][19] arginine, 20,21 calcium phosphate and its composites, [22][23][24][25][26][27][28][29][30][31] bioglass and silicates, [32][33][34][35][36][37][38][39][40][41][42][43] laser, 44,45 gallic acid (tannin)/Fe 3+ complex, 47,48 amyloid-like aggregation coating, 49 and selfassembly peptide. 51 Although some of these demonstrate clinical effectiveness in tooth desensitization, no treatment regimen presently exhibits long-lasting efficiency in treating DH.…”

Section: Introductionmentioning

confidence: 99%

Acidic Monetite Complex Paste with Bleaching Property for In-depth Occlusion of Dentinal Tubules

Liu¹,

Fang²,

Cao³

et al. 2021

IJN

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Nano/micro fluorhydroxyapatite crystal pastes in the treatment of dentin hypersensitivity: an in vitro study

Abstract: The tested materials may offer a long-term treatment for DH.

Cited by 17 publications

References 38 publications

A novel application of nano eggshell/titanium dioxide composite on occluding dentine tubules: an in vitro study

A novel application of nano eggshell/titanium dioxide composite on occluding dentine tubules: an in vitro study

Hydroxyapatite and Fluorapatite in Conservative Dentistry and Oral Implantology—A Review

Acidic Monetite Complex Paste with Bleaching Property for In-depth Occlusion of Dentinal Tubules

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