Nano isopolyoxomolybdate catalyzed Biginelli reaction for one-pot synthesis of 3,4-dihydropyrimidin-2(1H)-ones and 3,4-dihydropyrimidin-2(1H)-thiones under solvent-free conditions

Chitosan-silica Sulfate Nano Hybrid: An Efficient Biopolymer Based-heterogeneous Nano Catalyst for Solvent-free Synthesis of 3,4-Dihydropyrimidine-2(1H)-one/thiones

“…After optimizing the reaction conditions, we explored the versatility and generality of the present method for synthesis of structurally diverse 3,4-dihydropyrimidine-2(1H)-one/thione derivatives. Accordingly, 3CRs be- 47 [Btto][p-TSA], solvent-free, 90 °C 30 89 3 24 Dendrimer-PWA n , solvent-free, 80 °C 40 91 4 24 Dendrimer-PWA n , EtOH, 50 °C, ultrasound irradiation 10 90 5 48 Isopolyoxomolybdate, solvent-free, 110 °C 19 92 6 13 [TEAPS]H tween (thio)urea, methyl acetoacetate and different aldehydes were carried out in the presence of CSSNH under the solvent-free condition at 100 °C to produce the desired products 4a-s in good to excellent yields and also in short reaction times (Table 4).…”

Biginelli Reaction: Polymer Supported Catalytic Approaches

“…The reaction condition was optimized with respect to amount of catalyst, solvent, and temperature; the solvent-free condition suited the reaction best and furnished excellent yields of products. The recyclability of {Mo 132 } nanocatalyst was mentioned for six subsequent cycles . The protocol seems advantageous compare to other methods with shorter reaction time and excellent yields.…”

“…The recyclability of {Mo 132 } nanocatalyst was mentioned for six subsequent cycles. 270 The protocol seems advantageous compare to other methods with shorter reaction time and excellent yields. The {Mo 132 } (Table 12) nanocatalyst was found to be added as another efficient catalyst to the Biginelli synthesis.…”