Nano-hydroxyapatite reinforced zeolite ZSM composites: A comprehensive study on the structural and in vitro biological properties

Iqbal, Nida; Kadir, Mohammed Rafiq Abdul; Iqbal, Saman; Razak, Saiful Izwan Abd; Rafique, Muhammad; Bakhsheshi‐Rad, Hamid Reza; Idris, Mohd Hasbullah; Khattak, Muhammad Adil; Raghavendran, Hanumantha Rao Balaji; Abbas, Ali

doi:10.1016/j.ceramint.2016.01.107

Cited by 34 publications

(17 citation statements)

References 35 publications

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“…It is also reported in Iqbal et al (2016) study by SEM pictures that human osteoblast cells have normal morphology and connected to each other by digitations (Iqbal et al, 2016). Zeolite-hydroxy apatite samples were distributed with elongated morphology on the disc surface and cells had more developed filopodia, so the surface can support cell attachment and growth and had no negative effect on cell viability.…”

Section: Discussionmentioning

confidence: 73%

“…Bigger pores (>100μm) are needed in Alloplast s to supply enough oxygen level and angiogenesis for the bone structure; therefore, we used MBCP extract with the pore size of 1 to 2mm in this study. Iqbal et al (2016) in an experimental study on the effect of incremental concentration of Zeolite from 1% to 10% (Iqbal et al, 2016); observed an increase in human osteoblastic cell proliferation rate at 3-and 7-day time points.…”

Section: Discussionmentioning

confidence: 97%

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Zeolite as a Bone Bio-Modifier Carrier: An In-Vitro Study

Mousavi¹,

Nejad²,

Shamsoddin³

et al. 2019

JMBR

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Background: Zeolite is a microporous aluminosilicate compound which has been successfully used in tissue engineering. The effects of Zeolite on the morphology and functions of pre-osteoblastic MG-63 cells as new bone enhancer material is still unclear. Methods: In this vitro experimental study, MTT and Alizarin red staining test were performed on six groups of MG-63 cells which differed in Zeolite (Z) concentration and the presence or absence of Alloplast extract (A). Group A: 0.1μg/mL Z+A, Group B: 0.1μg/mL Z without A, Group C: 0.2μg/mL Z+A, Group D: 0.2μg/mL Z without A, Group E: 0.3μg/mL Z+A, Group F: 0.3μg/mL Z without A. There were also three control groups as positive control, negative control, and Alloplast control based on each related test. The data were analyzed by SPSS 20 via one-way ANOVA and Welch test. (P<0.05). Results: At 24 hours, results showed that solutions with 0.1μg/mL, 0.2μg/mL, and 0.3μg/mL Zeolite with or without Alloplast had significantly higher proliferation rates than positive control (distilled water) groups without Alloplast (p<0.001). At 72hours time point, the results showed significantly higher proliferation rates in the solutions with 0.1μg/mL, 0.2μg/mL, and 0.3μg/mL Zeolite with or without Alloplast compared to the positive control group without Alloplast (p<0.001). Conclusions: Zeolite can increase proliferation of MG-63 cells without presence of Alloplast; It seems that combination of Zeolite with Alloplast maybe enhancing proliferation and function of MG-63 cells.

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Section: Discussionmentioning

confidence: 73%

Section: Discussionmentioning

confidence: 97%

Zeolite as a Bone Bio-Modifier Carrier: An In-Vitro Study

Mousavi¹,

Nejad²,

Shamsoddin³

et al. 2019

JMBR

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“…LTA-type zeolite was used due to its ability to incorporate Ca 2+ cations, which are considered to have anticaries activity, since there are able to rebuilt the HA (hydroxyapatite), Ca 10 (PO 4 ) 6 (OH) 2 , structure [ 22 ]. Some studies had already described the use of zeolite–HA composites as promising bone tissue engineering applications [ 23 ] due to their biocompatibility, stability, and activity in the proliferation of the normal human osteoblasts. In the cited study [ 21 ], several parameters were evaluated for the synthesis of LTA zeolites.…”

Section: Zeolitesmentioning

confidence: 99%

Nanomaterials in Dentistry: State of the Art and Future Challenges

2020

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Nanomaterials are commonly considered as those materials in which the shape and molecular composition at a nanometer scale can be controlled. Subsequently, they present extraordinary properties that are being useful for the development of new and improved applications in many fields, including medicine. In dentistry, several research efforts are being conducted, especially during the last decade, for the improvement of the properties of materials used in dentistry. The objective of the present article is to offer the audience a complete and comprehensive review of the main applications that have been developed in dentistry, by the use of these materials, during the last two decades. It was shown how these materials are improving the treatments in mainly all the important areas of dentistry, such as endodontics, periodontics, implants, tissue engineering and restorative dentistry. The scope of the present review is, subsequently, to revise the main applications regarding nano-shaped materials in dentistry, including nanorods, nanofibers, nanotubes, nanospheres/nanoparticles, and zeolites and other orders porous materials. The results of the bibliographic analysis show that the most explored nanomaterials in dentistry are graphene and carbon nanotubes, and their derivatives. A detailed analysis and a comparative study of their applications show that, although they are quite similar, graphene-based materials seem to be more promising for most of the applications of interest in dentistry. The bibliographic study also demonstrated the potential of zeolite-based materials, although the low number of studies on their applications shows that they have not been totally explored, as well as other porous nanomaterials that have found important applications in medicine, such as metal organic frameworks, have not been explored. Subsequently, it is expected that the research effort will concentrate on graphene and zeolite-based materials in the coming years. Thus, the present review paper presents a detailed bibliographic study, with more than 200 references, in order to briefly describe the main achievements that have been described in dentistry using nanomaterials, compare and analyze them in a critical way, with the aim of predicting the future challenges.

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“…After the mineralization period, the scaffold was removed from the solution and rinsed with water prior to the drying process. The morphology of the scaffold was observed by means of SEM and the elemental analysis was done using EDX [27,28].…”

Section: In Vitro Bioactivity Of Bone Scaffoldsmentioning

confidence: 99%

Fabrication of Bone Scaffolds from Cockle Shell Waste

2019

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Bone scaffold is a three-dimensional structure composed of materials that could enhance bone regeneration. Bone scaffolds were prepared using freeze-drying by varying the cockle shell powder concentration where sodium alginate acted as matrix. The scaffolds were then characterized by X-ray diffraction, Fourier transform infrared spectroscopy, scanning electron microscopy, energy-dispersive X-ray spectroscopy, texture analyzer, and liquid displacement method. The bioactivity of the scaffolds was evaluated by immersion into a simulated body fluid solution. Cockle shell powder concentrations affected the bone scaffold characteristics. The increment of the powder concentrations improved the physicochemical properties and bioactivity of the scaffolds.

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Nano-hydroxyapatite reinforced zeolite ZSM composites: A comprehensive study on the structural and in vitro biological properties

Cited by 34 publications

References 35 publications

Zeolite as a Bone Bio-Modifier Carrier: An In-Vitro Study

Zeolite as a Bone Bio-Modifier Carrier: An In-Vitro Study

Nanomaterials in Dentistry: State of the Art and Future Challenges

Fabrication of Bone Scaffolds from Cockle Shell Waste

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