Nail as a window of systemic diseases

Abstract

Certain nail changes are specific for various dermatological disorders. In addition, examination of nails may also provide an insight into more sinister systemic manifestations in the form of both subtle as well as specific changes. These findings may present as a defect of various anatomical components of the nail unit; nail matrix, nail plate and/or nail bed or vasculature. This article is an attempt to equip the dermatologists with a foresight to suspect and diagnose the unapparent systemic connotations that may be possible by a simple but detailed nail examination.

Dermatological Manifestations in Renal Transplant Recipients: A Single-centre Prospective Follow-up Study

“…Beau çiz-gileri gibi KS kullanimi ile ilişkilendirilen diğer yan etkiler de olgularimizda mevcuttu. Beau çizgileri renal yetmezlik dahil sistemik hastaliklar, nutrisyonel eksiklikler ve antineoplastik ajan kullanimi gibi (36,37) çeşitli nedenlerle tirnak matriks fonksiyonunun geçici olarak duraklamasi ve sonuçta tirnak plağin-da ortaya çikan enlemesine çöküntüler olarak bilinir. Literatürde KS kullanimi ile Beau çizgilerinin oluşu-munu ilişkilendiren olgu sunumu bulunmaktadir (38) .…”

Onychomycosis Due to Arthrinium arundinis: A Case Report

“…Thirdly, the nail affection was preceded by a trauma to the toe by introducing a wooden splinter under the nail plate. It is likely that the trauma also led to development of Beau's line (14), which was present only on the border of the lunula of the infected nail plate. It must also be noted that our patient was diabetic, which might have favoured the infection (15).…”

Muehrcke's lines in a psoriatic patient: A possible association with acitretin therapy

“…Two transverse white lines parallel to lunula in nail bed, which is associated with chronic hypoalbuminemia states such as nephrotic syndrome, are called Muehrcke’s lines . They were first reported in 1956 by Muehrcke .…”