Nafion®-coated mesoporous Pd film toward remarkably enhanced detection of lactic acid

Abstract

Mesoporous metal films can detect biomarkers with high sensitivity.

Three-dimensional paper-based microfluidic electrochemical integrated devices (3D-PMED) for wearable electrochemical glucose detection

“…Naon layer is critical to remove interferents present in sweat. 27 Next, three mL of 5% chitosan solution in 3% acetic acid was cast and the electrode was le overnight at 4 C. Following, we dropped 2 mL of GOx (10 mg mL À1 ) on the working electrode surface to dry for two hours and dropped 3 mL of 5% chitosan solution in 3% acetic acid. Finally, 2 mL of Naon (Naon : ethanol ¼ 1 : 10) were drop-casted on the working electrode surface to dry and stored at 4 C for standby.…”

Evaluating the Possibility of Translating Technological Advances in Non-Invasive Continuous Lactate Monitoring into Critical Care

“…Baba et al [ 113 ] reported a sensor based on porous palladium film, which when used in conjunction with a Nafion membrane produced selective detection for lactate. However, these were not tested in a sweat solution and had a smaller linear range than required for a clinical setting.…”

Deposition of nanomaterials: A crucial step in biosensor fabrication

“…In another study, a hybrid composite of NiO NPs, PANI, and GO was deposited onto GCE using a two-step process [224]. Aniline and GO were mixed and coated on the surface of GCE followed by NiO NPs electrodeposition on aniline/GO/GCE in NiCl2 solution using a chronoamperometric process, which polymerized the aniline and deposited NiO NPs [249]; graphene embedded in a bowl-shaped PPy microcontainer was used for dopamine detection [250], Pt-incorporated fullerene-like ZnO nanospheres deposited onto GCE was used for cholesterol detection [251], Au NPs-rGO deposited onto GCE was used for determination of methylmercury (CH3Hg + ) in fish [252], and many more [253][254][255][256]. Notably, the direct electrodeposition of composite nanomaterials has been preferred for realizing the high conductivity and synergistic effect between the composite materials for biosensing applications.…”

“…To fabricate highly selective and sensitive glucose biosensors, GOx was immobilized on electrochemically deposited nanostructures, which presented excellent sensing performance during glucose detection[234][235][236][237][238][239][240]. However, the stability of such biosensors remains challenging due to the use of enzymes.In addition, electrochemically deposited nanomaterials onto electrode surfaces were used for a variety of biosensor applications[241][242][243][244][245][246][247][248][249][250][251][252][253][254][255][256]. For instance, electrochemical co-deposited cytochrome c and vertically aligned rGO onto GCE were used for H2O2 and Au nanostructures deposited onto an FTO substrate was used for Escherichia coli detection[245]; a two-dimensional (2D) MoS2 nanosheet onto Au-coated was used for nonesterified fatty acid biomarker monitoring[246]; iron terephthalate SPEs metal-organic framework onto GCE was used for H2O2 and nitrite detection[247]; cubic Cu2O nanocages loaded with Au NPs onto GCE was used for thrombin detection [248]; Nafion-coated mesoporous Pd film onto an Au substrate was used for detection of lactic acid…”