Naevoid hyperkeratosis of the nipple and areola in a man

Kubota, Yoshiki; Koga, Takeharu; Nakayama, J.; Kiryu, Hiroe

doi:10.1046/j.1365-2133.2000.03320.x

Cited by 41 publications

(39 citation statements)

References 14 publications

(22 reference statements)

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“…7 Some authorities have advocated the use of cryotherapy. 2 Excision of the affected areola and reconstruction with a split skin graft has been proposed but yet to be performed. 8 Hence, the mainstay of surgical management is currently restricted to shave excision or curettage.…”

Section: Discussionmentioning

confidence: 99%

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Treatment of Nevoid Hyperkeratosis of the Nipple and Areola by Shave Excision

Swan

Gwilym²,

Hollowood³

et al. 2004

Annals of Plastic Surgery

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The case is presented of a 29-year-old female who, at the age of 13 years, developed bilateral verrucous thickening of her areolae. Despite the condition causing her significant psychosocial morbidity, a specialist referral was initially denied on the grounds that no treatment was apparently available. The condition progressively deteriorated over the subsequent 14 years. She was eventually referred for a dermatology opinion, and the diagnosis of nevoid hyperkeratosis was made. Topical therapy with keratolytics was unsuccessful, and she was referred for a plastic surgery review. Bilateral shave excision of the lesion was performed under general anesthesia, with a satisfactory outcome and no evidence of recurrence at 10 months.

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Section: Discussionmentioning

confidence: 99%

“…It is more common in females, although there are reports of the condition in males. 2 The condition is characterized by a slowly growing verrucous thickening of the nipple and/or areola, with associated hyperpigmentation. Medical treatment is generally unrewarding, with a high risk of recurrence with cessation of therapy.…”

mentioning

confidence: 99%

Treatment of Nevoid Hyperkeratosis of the Nipple and Areola by Shave Excision

Swan

Gwilym²,

Hollowood³

et al. 2004

Annals of Plastic Surgery

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“…Conservative approach includes keratolysis as salicylic acid 6%, lactic acid lotion, topical steroids, topical trietinoin, oral vitamin A and calcipotriol 2.Non-conservative methods are cryotherapy,[7] laser[8] and surgery. [9]…”

Section: Discussionmentioning

confidence: 99%

Surgical approach for nevoid hyperkeratosis of the areola

Foustanos¹,

Panagiotopoulos²,

Diab³

et al. 2012

J Cutan Aesthet Surg

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Nevoid hyperkeratosis of the breast is a rare condition affecting the nipple, the areola or both. It appears in both sexes and it can by lateral or unilateral. It can also accompany other skin diseases or systemic conditions including malignancies. Treatment may not be easy due to aesthetic consequences but surgery seems to be the most preferable therapeutic option. We report such a case successfully managed by surgical intervention.

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“…Various treatment modalities have been reported including topical corticosteroids, topical calcitriol [19], topical and oral retinoids [20], topical keratolytics, surgical techniques including cryotherapy excision [14,15,21,22], radiofrequency ablation [23], and laser [24]. A case of NHNA was successfully treated with carbon dioxide laser [21] and no recurrence was seen.…”

Section: Case Reportmentioning

confidence: 99%

“…The lesions may involve the nipple, the areola, or both. Kubota et al, [15] reviewed 45 cases of nevoid hyperkeratosis in which 17% of cases involved the nipple, 25% of cases involved the areola, and the remaining 58% of cases involved both the nipple and the areola.…”

Section: Case Reportmentioning

confidence: 99%