Surgical approach for nevoid hyperkeratosis of the areola

Abstract

Nevoid hyperkeratosis of the breast is a rare condition affecting the nipple, the areola or both. It appears in both sexes and it can by lateral or unilateral. It can also accompany other skin diseases or systemic conditions including malignancies. Treatment may not be easy due to aesthetic consequences but surgery seems to be the most preferable therapeutic option. We report such a case successfully managed by surgical intervention.

Nevoid hyperkeratosis of the nipple mimicking a seborreic keratosis

“…4 It's first described in the medical literature by Tauber in 1923 as a benign dermatologic change in the nipple and areola, it may involve the nipple, the areola or both. 5 Approximately 50cases have been reported in the literature. 2 Its etiology remains poorly understood and thus its treatment is empirical with an unpredictable therapeutic outcome.…”

Radical treatment of extensive nevoid hyperkeratosis of the areola and breast with surgical excision after mild response to topical agents: A case report

“…She was reported as fully healed at postop day 10 and free from recurrence at 12-month follow-up. The other patient received a primary surgical management of a bilateral nevoid hyperkeratosis of the nipples and areolas with surgical shaving of the nipple and areola on one side, and surgical resection of the areola followed by reconstruction with full-thickness skin graft on the other side [18] . At 24-month follow-up there was no evidence of recurrence and the result is aesthetically valid.…”

Naevoid hyperkeratosis of the nipple and areola: an extensive form in two adolescent Filipino females

“…There are also reports of NHNA mimicking mycosis fungoides. 8 Although there are no known hormone alterations associated with NHNA, endocrinological factors have been suggested in its pathogenesis because NHNA predominantly occurs in adolescent girls with onset soon after menarche, 1,5,7 or in the third decade of life associated with pregnancy. 3 A few cases have been reported of NHNA in men, presenting after diethylstilbestrol therapy for prostatic adenocarcinoma.…”