“…SF is biological lubricant existing in almost all articular joints, components of which consist of blood plasma, proteins and various biochemical compounds [15]. As alternative specimen in forensic toxicological investigations, SFs have also been used for detecting methanol, ethanol and certain drugs such as opiates and cocaine [16][17][18][19]. However, the studies on distribution of involved drugs and/or its metabolites in SF specimens in intoxication cases are sporadic, and thus of the very limited number.…”