Nachweis eines CO‐bindenden Hämoproteins in <i>Candida guilliermondii</i>, Stamm H 17, nach Kultur auf <i>n</i>‐Alkanen

M, Tittelbach; Rohde, H.; Weide, H.

doi:10.1002/jobm.19760160209

Cited by 4 publications

(1 citation statement)

References 6 publications

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“…This system converts n-hexadecane into n-hexadecanol and palmitic acid (Schunck et al, 1978b). As in the case of C. tropicalis, cytochrome P-450 is induced by growth on n-alkanes (Tittelbach et al, 1976).…”

Section: Introductionmentioning

confidence: 90%

Hydroxylation of Alkanes and Fatty Acids in Saccharomycopsis lipolytica. Evidence for the Involvement of Cytochrome P-450

Marchal¹,

Metche²,

Vandecasteele³

1982

Microbiology

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_ _ _ _ _ _ _~ _ _ _~ ____Growth of the yeast Saccharomycopsis lipolytica on n-alkanes induced a hydroxylation system which, in the presence of NADPH and O,, converted lauric acid into u-hydroxylauric acid. The specific hydroxylation activity was lower with the physiological substrate n-hexadecane than with lauric acid. This system was particulate and did not act on Nand O-dealkylated compounds. It was strongly inhibited by CO and its enzymic activity was unstable. Because of the presence of cytochrome oxidase in the preparations, spectral demonstration of the presence of cytochrome P-450 was difficult but could be achieved with the techniques developed.

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Section: Introductionmentioning

confidence: 90%

Hydroxylation of Alkanes and Fatty Acids in Saccharomycopsis lipolytica. Evidence for the Involvement of Cytochrome P-450

Marchal¹,

Metche²,

Vandecasteele³

1982

Microbiology

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Regulation der mikrobiellen Alkanoxidation mit Hinblick auf die Produktbildung

Rehm

Reiff

1982

Acta Biotechnologica

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Catabolic pathways of long‐chain n‐alkanes in the range of C8 to C18 are demonstrated and results of investigation about the regulation of monoterminal oxidation are given: – Enzymes of monoterminal alkane oxidation usually are inducible – Several intermediates of alkane oxidation can inhibit the primary oxidation of concerned alkane –Substances, e.g. glucose and glycerol, which ordinary don't be developed in catabolic alkane reactions, in many cases have an inhibitory effect on alkane oxidation The regulation of catabolic pathways has a great influence on the formation of specific products This influence is demonstrated examplarily at the production of biotin, fatty acids and citric acid.

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The induction of cytochrome P‐450 in Lodderomyces elongisporus

Mauersberger¹,

Schunck²,

Müller³

1981

J of Basic Microbiology

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In the alkane‐utilizing yeast strain Lodderomyces elongisporus cytochrome P‐450 is induced by aliphatic hydrocarbons and to a lesser degree also by some of their derivatives. Cycloheximide and glucose inhibit the induction process, the former by inhibition of cytoplasmic translation, the latter presumably by catabolite repression. Among the nearly 40 checked compounds tetradecane and 1‐tetradecene are the most effective inducers. The branching of the alkyl chain as well as the terminal introduction of electrophilic atoms decrease the induction effect.

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Nachweis eines CO‐bindenden Hämoproteins in Candida guilliermondii, Stamm H 17, nach Kultur auf n‐Alkanen

Cited by 4 publications

References 6 publications

Hydroxylation of Alkanes and Fatty Acids in Saccharomycopsis lipolytica. Evidence for the Involvement of Cytochrome P-450

Hydroxylation of Alkanes and Fatty Acids in Saccharomycopsis lipolytica. Evidence for the Involvement of Cytochrome P-450

Regulation der mikrobiellen Alkanoxidation mit Hinblick auf die Produktbildung

The induction of cytochrome P‐450 in Lodderomyces elongisporus

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