N-Butyl Cyanoacrylate Versus Conventional Suturing for Fixation of Meshes in an Incisional Hernia Model

Dilege, Ece; Deveci, Uğur; Erbil, Yeşim; Dinççağ, Ahmet; Seven, Rıdvan; Özarmağan, Selçuk; Mercan, Selçuk; Barbaros, Umut

doi:10.3109/08941939.2010.481008

Cited by 27 publications

(27 citation statements)

References 19 publications

(17 reference statements)

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“…Some authors actually think that the staples cause the pain by pinching the peritoneum [4]. This has led to the use of absorbable staples and to attempts to affix the prosthesis with glue, but the long-term efficacy of these approaches has not been demonstrated [39][40][41].…”

Section: Discussionmentioning

confidence: 97%

Laparoscopic treatment of incisional hernia. State of the art in 2012

Moreau

Helmy

Vons

2012

Journal of Visceral Surgery

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Section: Discussionmentioning

confidence: 97%

Laparoscopic treatment of incisional hernia. State of the art in 2012

Moreau

Helmy

Vons

2012

Journal of Visceral Surgery

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“…Moreover, the high viscosity of semi‐synthetic adhesives prevents application over a large contact area during laparoscopic surgery . Synthetic cyanoacrylates adhesives have the advantages of fast fixation and adequate adhesive strength for hernia repair, but in vitro cytotoxicity due to formaldehyde release and in vivo tissue toxicity have been reported …”

Section: Discussionmentioning

confidence: 99%

“…However, fibrin glue has inadequate tensile and adhesive strengths compared with sutures or synthetic adhesives . In contrast, synthetic adhesives have mechanical properties suitable for repairing defects in tissues exposed to high tensile loads, such as the bladder and abdominal wall …”

Section: Introductionmentioning

confidence: 99%

Surface modification of polypropylene surgical meshes for improving adhesion with poloxamine hydrogel adhesive

Khanna

Luzinov

et al. 2018

J Biomed Mater Res

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Tissue adhesive has notable clinical benefits in hernia repair fixation. A novel poloxamine tissue adhesive was previously shown to successfully bond collagen tissue with adequate adhesive strength. In application related to attachment of polypropylene (PP) mesh, the adhesive strength between the mesh and poloxamine hydrogel adhesive is limited by the hydrophobicity of PP monofilaments and lack of covalent bond formation. The purpose of this study was to compare two different surface modifications [bovine serum albumin (BSA) adsorption and poly-glycidyl methacrylate/ human serum albumin (PGMA/HSA) grafting] of PP mesh for improving the adhesive strength between poloxamine hydrogel adhesive and PP mesh. The PGMA/HSA surface modification significantly improved the adhesive strength for meshes attached with poloxamine hydrogel tissue adhesive compared with unmodified meshes and meshes modified by BSA adsorption. An area of 1 cm 2 adhesive provided for a maximum adhesive strength of 65-70 kPa for meshes modified by PGMA/HSA, 4-13 kPa for meshes modified by BSA, and 22-45 kPa for unmodified meshes. Optical microscopy and infrared spectroscopy (FTIR) confirmed the improved adhesive strength was achieved through mechanical interlock of the hydrogel tissue adhesive into the PP mesh pores and chemical bonding of the albumin after successful PGMA/HSA grafting onto the PP monofilaments.How to cite this article: Lu X, Khanna A, Luzinov I, Nagatomi J, Harman M. 2019. Surface modification of polypropylene surgical meshes for improving adhesion with poloxamine hydrogel adhesive. J Biomed Mater Res

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“…Bu sebeplerle üretilen, emilebilir zımbaların, kronik ağrıda anlamlı olarak avantajlı olduğu görülmüş ve yaygın olarak kullanılmaya başlanmıştır. Ayrıca literatürde, yama sabitlemede yapıştırıcı kullanımının tartışıldığı birkaç çalışma mevcuttur fakat henüz uzun dönem hiçbir sonuç yayınlanmamıştır (13)(14)(15).…”

Section: Discussionunclassified