Myxomas of the head and neck

Isolated Myxoma in the External Auditory Canal of a 10-Year-Old Girl

“…In 1871, Virchow used the term "myxoma" first for a tumor that histologically resembled the mucinous tissue of the umbilical cord [9] . However, in 1948, Stout established the generally accepted diagnostic criteria of myxoma as a true neoplasm that is composed of stellate cells that are set in a loose mucoid stroma through which course very delicate reticulin fibers in various directions [10] .…”

“…In the English literature, the sites of myxoma in the head and neck area have been various, including the maxilla, mandible, and oral cavity [7,9] . Ten cases of myxoma in the head and neck area, including the maxilla, larynx and neck, have been reported in the Korean literature.…”

Laryngeal Myxoma: A Case Report and Review of the Literature

“…Although myxomas are well-circumscribed, they lack a fibrous capsule and tend to grow via local infiltration [6].…”

“…Stout provided support for myxomas being neoplastic and established diagnostic criteria [2]. Laryngeal myxomas display a strong male predilection, with nine out of the ten reported cases occurring in males, in contrast to elsewhere in the head and neck where myxomas predominate in females [6]. More than half of patients with laryngeal myxomas have a smoking history although it is uncertain however, whether smoking plays a role in the development of these neoplasms.…”

“…Myxomas of the head and neck have been reported in adolescents and young adults. Pediatric patients most commonly present with myxomas of the mandible [6].…”