The OBJECTIVE of this study was to demonstrate and original clinical case of an appendiceal mucocele, complicated by intussusception in a 45-year-old female patient.METHODS AND MATERIALS. We present a rare clinical case of appendiceal mucocele in a female patient, complicated by partial intussusception into the caecum. Diagnostic laparoscopy was performed, followed by laparotomy with reduction of the intussusception and an atypical appendectomy.RESULTS. In this article we present a review of the literature and analyze our clinical case. Treatment result was positive, postoperative period was uncomplicated. This patient was followed up for year postoperatively.